颞叶癫痫的显微外科治疗  

Microsurgery for treatment of intractable temporal epilepsy

作　　者：高觉民[1] 李铭[1] 胡静[1] 汤忠华[1] 樊炼[1] 傅传经[1] 叶明[1] 李建[1] 谭启富[2] 史德志[1] 吴颐[1] 

机构地区：[1]江苏省中医院神经外科,210029 [2]南京军区总医院神经外科

出　　处：《临床神经外科杂志》2014年第4期286-288,共3页Journal of Clinical Neurosurgery

摘　　要：目的：探讨颞叶癫痫的术前评估及显微外科治疗方法。方法选择73例颞叶癫痫患者，根据病史、影像学、电生理等资料进行术前评估，采用改良的显微外科前颞叶切除术并根据癫痫灶的定位和性质术中微调整。结果本组患者术后随访半年～两年，满意54例（74％），显著改善（癫痫发作减少75％以上）11例（15％），良好（癫痫发作减少50％以上）6例（8％），效果差或无改善2例（3％）。结论术前评估明确后，外科手术治疗难治性颞叶癫痫是一种安全、有效的方法。对致痫灶的综合精确定位和彻底处理是提高疗效的关键。Objective To explore the methods of preoperative diagnosis and minimally invasive surgery of temporal lobe epilepsy .Methods Total 73 cases with temporal lobe epilepsy were assessed by comprehensive preoperative-evaluation of medical history , neuroimaging and electrophysiology examination .And improved anterior temporallobectomy was guided according to epileptogenic lesions .Results All patients were followed up for 0.5 to 2 years,54 got satisfied （74%）,11 cases were improved significantly （15%）,6 improved（8%） and 2 were invalid（3%）. Conclusions The effect of surgical treatment of refractory temporal lobe epilepsy is secure and satisfactory through comprehensive preoperative-evaluation. Achieving accurate location of epileptogenic focus and performing sufficient excision of epileptogenic focus is the key point of improve curative effect .

关 键 词：颞叶癫痫 外科治疗 术前评估 

分 类 号：R742.1[医药卫生—神经病学与精神病学]