复方枸橼酸阿尔维林治疗功能性腹痛综合征的疗效  

Clinical efficacy of compound alverine citrate in treatment of functional abdominal pain syndrome

作　　者：刘宁[1] 练海燕[1] 郭伟强[1] 潘美云[1] 

机构地区：[1]柳州市人民医院消化内科,广西壮族自治区柳州市545006

出　　处：《世界华人消化杂志》2014年第18期2641-2644,共4页World Chinese Journal of Digestology

摘　　要：目的:观察复方枸橼酸阿尔韦林治疗功能性腹痛综合征(functional abdominal pain syndrome,FAPS)的疗效、费用和不良反应.方法:67例功能性腹痛综合征患者随机分为两组,分别口服复方枸橼酸阿尔韦林软胶囊、马来酸曲美布汀分散片治疗,共6 wk,评价疗效、费用-效益比(C/E)及药物不良反应.结果:研究组治疗总有效率明显优于对照组,分别为75.76%和30.00%(P<0.01).研究组腹痛评分较治疗前显著下降(P<0.01),且显著低于对照组治疗后评分(P<0.05).两组患者均未发现严重不良反应.结论:复方枸橼酸阿尔韦林治疗功能性腹痛综合征疗效显著且不良反应发生率低.AIM： To investigate the efficacy, cost-effectiveness and adverse reactions of compound alverine citrate in treating patients with functional abdominal pain syndrome（FAPS）.METHODS： Eighty-two patients with FAPS were randomized into a study group and a control group to receive compound alverine citrate soft capsules and trimebutine maleate, respectively, for 6 wk. The efficacy, cost-effectiveness ratio and adverse reactions were compared between the two groups. RESULTS： The overall response rate in the study group was superior to that in the control group（75.76% vs 30.00%, P〈0.01）. The abdominal pain score in the study group was decreasedsignificantly compared with pretreatment value（P〈0.01）. The abdominal pain score in the study group was significantly lower than that in the control group（P〈0.05）. No adverse reactions were found in this study.CONCLUSION： Compound alverine citrate is effective in treating FAPS patients with few adverse reactions.

关 键 词：复方枸橼酸阿尔韦林 功能性腹痛 费用效益 药物不良反应 

分 类 号：R57[医药卫生—消化系统]