树突细胞/细胞因子诱导的杀伤细胞治疗肺癌33例临床分析  

Clinical Analysis of 33 Cases of Lung Cancer Treated with Dendritic Cells/Cytokine Induced Killer Cell Therapy

作　　者：李建忠[1] 高峰[1] 梁兵[1] 马朝晖[1] 

机构地区：[1]解放军第211医院胸心外科,黑龙江哈尔滨150000

出　　处：《创伤与急危重病医学》2014年第4期237-238,共2页Trauma and Critical Care Medicine

摘　　要：目的探讨树突细胞/细胞因子诱导的杀伤细胞（DC/CIK）在治疗肺癌中的作用。方法对33例恶性肿瘤患者行DC/CIK方法治疗,观察近期效果。结果 33例DC/CIK培养均获成功。在生物治疗方法下观察8-10个月,血液中免疫细胞大幅增加,肿瘤标记物下降,与治疗前相比,差异有统计学意义,P〈0.05。结论生物治疗（DC/CIK）作为恶性肿瘤的新疗法,对恶性肿瘤有一定的治疗作用。Objective To investigate the role of DC /CIK in the treatment of lung cancer and provide reference for the application of this technology. Methods 33 casts of patients with lung cancer were treated with DC /CIK,and the near- term results of all cases were observed. Results 33 cases of DC /CIK were successfully cultured. 33 cases were observed under the biological treatment from 8 to 10 months. Immune cells substantially increased and tumor markers decreased in the blood（P〈0. 05,compared with pre- treatment）. Conclusion The biological treatment（ DC /CIK） is a new therapy that plays a certain role for the treatment of lung cancer.

关 键 词：肺癌 生物治疗 树突状细胞 细胞因子诱导的杀伤细胞 

分 类 号：R730.54[医药卫生—肿瘤] R734.2[医药卫生—临床医学]