液基细胞学技术在颈部非甲状腺肿块针吸细胞学中的应用  

Application of liquid-based preparations in fine needle aspiration for identifying non-thyroid neck masses

作　　者：程柳柳[1] 李俊[1] 仲飞[1] 

机构地区：[1]安徽医科大学第一附属医院肿瘤内科,合肥市230001

出　　处：《实用医学杂志》2014年第17期2748-2750,共3页The Journal of Practical Medicine

基　　金：安徽省自然科学研究重点项目(编号:KJ2012A163)

摘　　要：目的:比较液基细胞技术(liquid-based preparations,LBP)和传统制片技术(conventional smears,CS)在颈部非甲状腺肿块穿刺标本中的诊断价值。方法:从493例颈部非甲状腺肿块穿刺标本的涂片质量和诊断准确度等方面对2种制片方法进行比较分析。结果:LBP的不满意率为13.0%,低于CS的16.0%(P<0.05)。同时LBP的敏感度和准确度分别为94.6%和96.8%,而CS分别为92.9%、95.0%。在涂片质量方面,LBP具有细胞数量多,背景清晰,细胞形态容易辨认的优点。结论:LBP在诊断颈部非甲状腺肿块中有优势,尤其在诊断颈部淋巴结时优势明显,但是在唾液腺肿块的诊断中并无明显优势。Objective To compare the value of liquid-based preparations versus conventional smears in thediagnosis of non-thyroid neck masses from fine needle aspiration. Methods The two different methods were comparedby the smear quality and the diagnostic accuracy for the aspiration samples of non-thyroid neck masses of 400patients. Results The unsatisfactory rate for LBP was lower than that for CS （ 13.0% vs. 16.0%, P 〈 0.05）. Thesensitivity was 94.6% for LBP and 92.9% for CS, and the accuracy was 96.8% for LBP and 95.0% for CS. In theaspect of smear quality, LBP had advantages of quantity of cells, with clear background and easily identifiable cellmorphology. Conclusions LBP has more advantages than CS in the identification of non-thyroid neck masses,especially for cervical nodal enlargement. But it has no marked advantages in the diagnosis of salivary gland lesions.

关 键 词：针吸细胞学 颈部非甲状腺肿块 液基细胞学 传统细胞学 

分 类 号：R739.91[医药卫生—肿瘤]