丁苯肽注射液治疗短暂性脑缺血发作的效果研究  

Effect of butylphthalide injection on transient ischemic attack

作　　者：田强元[1] 齐鹏[2] 王志敏[3] 

机构地区：[1]山东省滨州市人民医院神经内科,256610 [2]山东省滨州市人民医院康复科,256610 [3]山东省滨州市人民医院血液科,256610

出　　处：《中国实用医刊》2014年第18期24-25,共2页Chinese Journal of Practical Medicine

摘　　要：目的：研究丁苯肽注射液治疗短暂性缺血发作的临床效果。方法选择2012年3月至2013年3月于滨州市人民医院治疗的短暂性脑缺血发作患者136例，将其随机分为两组，每组68例。在对患者的血糖及血压进行调控的基础上，常规组给予阿司匹林、奥扎格雷钠、低分子肝素、丁咯地尔抗凝、抗血小板聚集及扩血管治疗。观察组以常规组治疗为基础，加用丁苯肽注射液静脉滴注。比较两组患者的临床治疗效果。结果观察组经治疗后，总有效率为97.06%，常规组经治疗后，总有效率为85.29%，两组差异有统计学意义（ P﹤0.05）。结论丁苯肽注射液可显著减少短暂性缺血发作患者的发作次数，临床疗效确切。Objective To investigate the clinical effect of butylphthalide injection on transient ischemic attack. Methods From March 2012 to March 2013,136 cases of transient ischemic attack treated in Binzhou people’s hospital were chose,and the patients were randomly divided into two groups, each group with 68 cases. On the basis of controlling and regulating the blood glucose and blood pressure levels of the patients,the patients in convention group were given aspirin,sodium ozagrel,low molecular weight heparin,buflomedil for anticoagulation,anti-platelet aggregation,and vasodilator therapy. Pa-tients in the observation group were given butylphthalide injection for intravenous drip,on the basis of the treatment in convention group. The clinical treatment effects were compared between the two groups. Re-sults After treatment,the total effective rate in the observation group was 97. 6%,and that in the con-vention group was 85. 29%,there was significant difference（ P﹤0. 05 ）. Conclusions Butylphthalide injection can significantly reduce the attack number of transient ischemic attack,and the clinical effect is good.

关 键 词：丁苯肽注射液 短暂性脑缺血发作 效果 

分 类 号：R743.3[医药卫生—神经病学与精神病学]