腔内支架成形术治疗椎动脉狭窄的疗效观察  

Effect Observation of Endovascular Stenting in Treatment of Vertebral Artery Stenosis

作　　者：杨永[1] 张雪玲[1] 李丹[1] 蔡旺[1] 张建永[1] 朱宗锦[1] 

机构地区：[1]南京鼓楼医院集团宿迁市人民医院,江苏宿迁223800

出　　处：《中国医学创新》2014年第23期124-126,共3页Medical Innovation of China

摘　　要：目的:探讨血管内支架成形术对治疗椎动脉狭窄的临床安全性以及疗效,为该治疗手段在临床的应用提供可靠的证据。方法:选取合适支架植入的40例经影像学检测确诊为椎动脉狭窄并且用常规药物治疗无效的患者,术后即刻经磁共振血管造影(Magnetic resonance angiography,MRA)和血管造影技术测量,比较手术前后椎动脉狭窄的程度,并在术后进行跟踪随访,评价其临床疗效。结果:经过手术,40例确诊的椎动脉狭窄患者血管腔内成功植入了支架。术后椎动脉平均狭窄程度明显降低,平均狭窄率由术前的74.6%下降到13.2%。临床随访中未发现复发血管再狭窄以及血管内膜撕裂或血栓栓塞等并发症。结论:经临床研究证明,血管内支架成形术治疗椎动脉狭窄具有确切的疗效,但对于患者远期预后仍需要更长时间随访和大宗病例进行评估。Objective：To evaluate clinical safety and efficacy of endovascular stenting in treatment of vertebral artery stenosis,and further provide reliable evidence for the clinical application of treatment.Method：40 patients with vertebral basilar artery stenosis diagnosed by DSA and with no effect of common agents were treated with the endovascular stenting. Magnetic resonance angiography and Coronary Angiography Technique were administered to detect the degree of vertebral artery stenosis before and after surgery,and postoperative follow-up track to evaluate its clinical efficacy. Result：After surgery,40 patients treated with endovascular stenting were successful. The average postoperative vertebral artery stenosis was significantly lower,74.6%of the average rate of preoperative stenosis decreased to 13.2%. Clinical follow-up found no recurrence of restenosis and vascular intimal tear or thromboembolic complications. Conclusion：Clinical studies have shown that endovascular stenting has the exact effect of vertebral artery stenosis,but long-term prognosis of patients still need more time to assess follow-up and the bulk of cases.

关 键 词：椎动脉狭窄 血管内支架成形术 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]