造血干细胞移植后真菌感染病例分析  

Hematopoietic stem cell transplantation Preliminary fungal infections

作　　者：张培利[1] 刘永青[1] 

机构地区：[1]郑州市第三人民医院,河南郑州450000

出　　处：《饮食保健》2014年第2期62-65,共4页Diet Health

摘　　要：目的探讨造血干细胞移植（HSCT）后的真菌感染特征。方法对84例接受造血干细胞移植的患者移植后合并真菌感染的原发病、移植方式、抗真菌治疗的反应进行分析。结果84例患者中．合并真菌感染25例，其中自身免疫性疾病11例，4例为未进行CD34纯化自体造血干细胞移植．7例为CD34纯化自体造血干细胞移植；恶性血液病14例，2例为自体造血干细胞移植，12例为异基因造血干细胞移植。死亡5例．3例为自身免疫性疾病；2例为恶性血液病，均为异基因造血干细胞移植。结论真菌感染的风险除与移植方式有关外，原发病与真菌感染亦有显著相关性。抗真菌药物治疗时机与选择可能影响预后。objective： to research Characteristics of fungal infections after allogeneic hematopoietic stem cell transplantation （Allo-HSCT） Methods：Of 84 patients who received hematopoietic stem cell transplantation in patients with fungal infection after transplantation, original disease, transplant method, anti-fungal treatment response analysis. Results： 84 patients, the fungal infection in 25 cases, including autoimmune diseases, 11 cases, 4 were not for CD34 purified autologous stem cell transplantation, 7 were CD34 purified autologous stem cell transplantation; hematologic malignancies in 14 cases, 2 cases Autologous hematopoietic stem cell transplantation, 12 cases of allogeneic hematopoietic stem cell transplantation. 5 deaths, 3 cases of autoimmune diseases; 2 cases of hematologic malignancies, both allogeneic hematopoietic stem cell transplantation.Conclusions： In addition to the risk of fungal infections mmng an and transplant the way, the primary disease and fungal infections are also a significant correlation. The d choice of antifungal therapy may affect the prognosis.

关 键 词：造血干细胞移植 真菌 感染 

分 类 号：R733[医药卫生—肿瘤]