PRK术后合理使用激素的探讨  

Discussion about Application of steroids after

作　　者：周希瑗[1] 陈曜[1] 陈辉[1] 杜之渝[1] 

机构地区：[1]重庆医科大学附二院眼科,400010

出　　处：《中国实用眼科杂志》2002年第8期603-605,共3页Chinese Journal of Practical Ophthalmology

摘　　要：目的 :探索PRK术后使用非甾体激素类药物代替部分激素的有效性及安全性。方法 :选择条件相同的PRK手术眼 80例 ,术后 5天开始点用眼药 ,40例单用艾佛龙 (A组 ) ,40例用艾佛龙 +安贺拉 (B组 ) ,激素用药逐日减少 ,以次 /日·月计数 ,其中A1(<-6 0 0D .S)为 4,3 ,2 ,1;A2 (>6 0 0D .S)为 4,3 ,3 ,2 ,2 ,1;B1(<6 0 0D .S)为 3 ,2 ,1;B2 (>6 0 0D .S)为 4,3 ,2 ,1。安贺拉均为 3次 /日。术后 1,3 ,6个月随访视力、屈光度、Haze及眼压变化。结果 :A组与B组相比 ,眼压升高有显著差异 ,其余视力、屈光度、Haze均无显著差异 ,说明由于B组用激素次数少、时间短 ,发生激素性高眼压的可能性要小。结论 :PRK术后早期应用非甾体类抗炎药可以减少激素用量 ,减少激素性高眼压的发生 ,而对PRK术后控制屈光回退、Haxe的发生是行之有效的。To investigate the efficiency and safety of no nsteroid anti inflammatory drugs after photorefractive keratectomy (PRK). Methods:Under the agreement of patients,80 post PRK eyes were divided into 2 groups;A group was only managed by Fluorometholone,B group was by fluorometholone combining with Acular (3 times per day).Visual acuity,diopter,haze,intraocular pressure were Checked in 1m,3m,6m after operation. Results:The intraocular pressure in A group was significan tlyhigher than that in B group,but there were no significant differences in visu al acuity,diopter or haze between A and B groups. Conclusions:With early application of non steroid medicin e,the dose and the side effects of steroid can be reduced,such as the possibility of steroid induced high intraocular pressure might be reduced.But the application of non steroid medicine seems no impacts on the others,for example the,the management effect of steroid for haze.

关 键 词：PRK 非甾体类药物 准分子激光角膜切削 手术后激素 合理用药 

分 类 号：R779.63[医药卫生—眼科] R977.1[医药卫生—临床医学]