糖尿病增强环境物理因素致健康损伤效应的研究现状  

Diabetes Aggravates Physical Factor-Induced Health Effects: An Overview

作　　者：李芳[1] 严颖[1] 宋菁菁[1] 韦娟[1] 王苏华[1] 陆荣柱[1] 

机构地区：[1]江苏大学医学院卫生检验系,江苏212013

出　　处：《环境与职业医学》2014年第8期631-633,共3页Journal of Environmental and Occupational Medicine

基　　金：国家自然科学基金(编号:81302459);中国博士后科学基金(编号:2013M540424);江苏大学高级专业人才科研启动基金项目(编号:13JDG024);江苏省博士后科学基金(编号:1302151C)

摘　　要：糖尿病可改变极端气温条件下的体温调节能力,患者在极端低温和高温下生活,遭受冷损伤或热损伤的风险将比健康人群更大;糖尿病可能会延迟暂时性噪声性听力损失的修复能力和加重永久性噪声性听力损失;糖尿病大鼠对电磁场致血脑屏障功能的损伤也比健康大鼠的更严重。因而提示,糖尿病可增强环境物理因素的健康损伤,其机制可能涉及氧化应激、出汗障碍和血流收缩功能异常,因而糖尿病患者这一特殊易感人群需要相应的防护措施。Diabetes can deteriorate the ability to adjust body temperature under extreme conditions so that the risk of cold damage or thermal damage would increase in diabetic patients exposed to extreme temperatures. Diabetes may also delay the ability to repair temporary noise-induced hearing loss and aggravate permanent noise-induced hearing loss. Animal experiments show that the damages of blood brain barrier induced by electromagnetic fields increase in diabetic rats. The action mechanisms of diabetes patients deteriorating the adverse health effects induced by environmental physical factors are related to oxidative stress, sweating disorders, and abnormal blood flow. Specific policies are warranted for protection of diabetic patients from environmental physical factors.

关 键 词：糖尿病 环境物理因素 健康损伤 作用机制 

分 类 号：R730.231.2[医药卫生—肿瘤]