非肌层浸润性膀胱癌26例治疗分析  

Treatment of Non-Muscle-Invasive Bladder Cancer:An Analysis of 26 Cases

作　　者：王月生 

机构地区：[1]铜陵市市立医院泌尿外科,安徽铜陵244000

出　　处：《实用临床医学（江西）》2014年第6期41-43,共3页Practical Clinical Medicine

摘　　要：目的：探讨非肌层浸润性膀胱癌的治疗方法和疗效。方法对26例非肌层浸润性膀胱癌患者行经尿道电切术或膀胱部分切除术，术后辅以膀胱药物灌注治疗。结果26例均一次手术将肿瘤完全切除，25例均定期行膀胱药物灌注化疗。1例行输尿管口电切的患者术后未发生同侧输尿管口狭窄、膀胱输尿管返流。术中未发生大出血、严重膀胱穿孔等并发症。术后26例患者均获得随访，随访时间为5～43个月：23例均无瘤存活，3例患者死于其他疾病；其中4例复发，复发率为15.4%；4例复发患者，2例再次行TURBT术，2例行膀胱部分切除术。结论经尿道电切术或膀胱部分切除术辅以术后灌注化疗是非肌层浸润性膀胱癌的一种有效治疗方法，其安全性高，并发症少，疗效确切，且没有增加肿瘤复发或进展的风险。Objective To explore the treatment of non-muscle-invasive bladder cancer. Methods Twenty-six patients with non-muscle-invasive bladder cancer underwent transurethral resection or partial cystectomy supplemented with postoperative bladder perfusion chemotherapy. Results Tumors were completely resected at the first attempt in all the 26 patients and bladder drug perfusion were regularly performed in 25 patients. One patient who underwent transurethral incision of the ureteral orifice had no ipsilateral ureteral orifice stricture and vesicoureteric reflux. No intraoperative massive haemorrhage, severe bladder perforation and other complications occurred in all patients. All patients were followed up for 5-43 months. Among the 26 patients, 23 had disease-free survival, and 3 died of other diseases. The recurrence rate was 15.4%. Among the 4 patients with recurrence, transurethral resection of bladder tumor was performed again in 2, and partial resection of the bladder in 2. Conclusion Transurethral resection or partial cystectomy supplemented with postoperative bladder perfusion chemotherapy is an effective treatment for non-muscle-invasive bladder cancer and results in high safety, fewer complications and precise curative effect without increased risk of tumor recurrence or progression.

关 键 词：非肌层浸润性膀胱癌 经尿道电切术 膀胱部分切除术 膀胱药物灌注 

分 类 号：R737.14[医药卫生—肿瘤]