台盼蓝囊膜染色剂在复明工程成熟期白内障手术撕囊中的应用  

Application of trypan blue lens capsule staining for cataract surgery in Vision Recovery Project

作　　者：宋万卿 韦秀娟 栾丽利 

机构地区：[1]河北省兴隆县人民医院眼科,承德067300

出　　处：《眼科》2014年第4期271-273,共3页Ophthalmology in China

摘　　要：目的探讨台盼蓝囊膜染色剂在白内障复明工程白内障手术撕囊中的应用价值。设计回顾性比较性病例系列。研究对象2012-2013年期间河北省兴隆县人民医院"百万贫困白内障患者复明工程"成熟期或过熟期白内障手术患者84例(84眼)。方法随机分为观察组和对照组,每组42例(42眼)。观察组超声乳化白内障手术过程中接受0.1 ml 0.1%台盼蓝磷酸盐缓冲溶液前囊膜染色后行连续环形撕囊,对照组超声乳化白内障术中撕囊前未予染色。主要指标术中囊膜染色情况,撕囊成功率,术后视力、眼压、前房炎症反应、角膜水肿及后囊混浊情况。结果观察组台盼蓝染色后,晶状体前囊膜100%被染成淡蓝色。撕囊成功率观察组97.6%,对照组78.6%(P=0.003);术后1个月视力、眼压、前房炎症反应、角膜水肿情况两组比较差异无统计学意义(均为P>0.05);术后3个月后囊膜明显混浊观察组1/42例、对照组6/42例(P=0.027)。结论白内障复明工程成熟期或过熟期白内障手术中采取台盼蓝囊膜染色剂行前囊膜染色,使连续环形撕囊相对容易,保证手术更顺利进行。Objective To explore the application value of trypan blue lens capsule staining in cataract surgery in Vision Recovery Project. Design Retrospective comparative case series. Participants 84 patients （84 eyes） with severe cataract in “Vision Recovery Pro- ject of Millions of Poor Cataract Patients” in 2012-2013 were recruited. Methods Patients were randomly divided into observation group（42 patients, 42 eyes） and control group（42 patients, 42 eyes）. Observation group received 0.1 ml trypan blue capsule staining be- fore continuous eurvilinear capsulorhexis during phacoemulsification, but control group were not stained. Main Outcome Measures State of intraoperative lens capsule staining, success rate of continuous curvilinear capsulorhexis, visual acuity, intraoeular pressure, de- gree of anterior chamber inflammation, corneal edema and posterior capsular opacification. Results The lens anterior capsule of all pa- tients in observation group was stained as light blue after the trypan blue staining. The success rate of continuous curvilinear capsu- larhexis was 97.6% in observation group and 78.6% in control group （P=0.003）. The difference of visual acuity, intraoeular pressure, anterior chamber inflammation, corneal edema after surgery were no statistically significant （all P〉0.05）. 3 months after surgery, significant posterior capsular opaeification appeared in one case in observation group and six cases in control group （P=0.027）. Conclusion The continuous circular capsulorhexis and phacoemulsification in Vision Recovery Project could become easier to perform after anterior capsule staining with trypan blue.

关 键 词：白内障 台盼蓝 连续环形撕囊 

分 类 号：R779.66[医药卫生—眼科]