Predictors of anti-vascular endothelial growth factor treatment responses in macular edema following central vein occlusion  

作　　者：Huang Peirong Song Zhengyu Sun Xiaodong 

机构地区：[1]Department of Ophthalmology, Shanghai First People's Hospital,School of Medicine, Shanghai JiaoTong University, Shanghai200080, China [2]Shanghai Key Laboratory of Fundus Disease, Eye Research Instituteof Shanghai Jiao Tong University, Shanghai 200080, China

出　　处：《Chinese Medical Journal》2014年第16期3019-3023,共5页中华医学杂志（英文版）

基　　金：This study was supported by tgrants from the National Basic Research Program of China ＂973 Program＂ （No. 2011CB707506）, the National Natural Science Foundation of China Grant （No. 81271030）, Shanghai Key Basic Research Grant （No. 11JC141601）, Shanghai Scholar Leadship Grant （No. 12XD1404100 and No. XBR2013081） and Shanghai Creative Key Medical Research Grant （No. 1341195400）.

摘　　要：Retinal vein occlusion （RVO） ranged the second common cause of retinal vascular disease, consisting of central retinal vein occlusion （CRVO） and branch retinal vein occlusion （BRVO） Although the prevalence of CRVO was one-third of BRVO, it associated with worse prognosis both before and after the anti-vascular endothelial growth factor （VEGF） regimes came into clinic use. A recent pooled age- and sex-standardized analysis showed that the prevalence was 0.8 per 1 000 （CI： 0.61-0.99） for CRVO around the world. Similarly, in our country, the 10-year incidence of CRVO in Beijing （2001-2011） was 0.3±0.1 per 100 persons.Retinal vein occlusion （RVO） ranged the second common cause of retinal vascular disease, consisting of central retinal vein occlusion （CRVO） and branch retinal vein occlusion （BRVO） Although the prevalence of CRVO was one-third of BRVO, it associated with worse prognosis both before and after the anti-vascular endothelial growth factor （VEGF） regimes came into clinic use. A recent pooled age- and sex-standardized analysis showed that the prevalence was 0.8 per 1 000 （CI： 0.61-0.99） for CRVO around the world. Similarly, in our country, the 10-year incidence of CRVO in Beijing （2001-2011） was 0.3±0.1 per 100 persons.

关 键 词：retinal vein occlusion macular edema vascular endothelial growth factor visual acuity 

分 类 号：R774.5[医药卫生—眼科]