纵隔淋巴瘤出现坏死的特点及相关因素分析  

Feature and related factor analysis of mediastinal lymphoma with necrosis

作　　者：张文浩[1] 叶丽芳[1] 雷永霞[1] 周润婷[1] 莫森林 蒙秋华[1] 

机构地区：[1]广州医科大学附属第一医院放射科,广东广州510120

出　　处：《实用放射学杂志》2014年第8期1310-1312,1399,共4页Journal of Practical Radiology

摘　　要：目的：探讨纵隔淋巴瘤出现坏死的相关因素及特点,以鉴别其他出现坏死的纵隔肿瘤。方法收集37例经病理学证实纵隔淋巴瘤患者资料,回顾性观察其 CT 征象并分析发生坏死的相关因素。结果37例均表现为纵隔软组织肿块,25例跨区生长,11例位于前纵隔,1例位于后纵隔；肿瘤最大截面积为1.6~129.6 cm^2,其中1例最大截面积为0~10 cm^2,8例为10~25 cm^2,10例为25~50 cm^2,15例为50~100 cm^2,3例〉100 cm^2；24例发生坏死,13例无坏死；发生坏死的24例中,23例轻~中度强化,1例明显强化。经 Logistic 回归分析,病灶大小和增强实质期 CT 净增值与病灶有无坏死有关（P 〈0.05）。结论纵隔淋巴瘤出现坏死并不少见,病灶大小和增强实质期 CT 净增值与病灶有无坏死相关,轻~中度强化是淋巴瘤与其他出现坏死的纵隔肿瘤的鉴别要点之一。Objective To analyze CT features and related factors of mediastinal lymphoma with necrosis in order to identify other mediastinal tumor with necrosis.Methods CT features were retrospectively reviewed and related factors of necrosis were analyzed in 37 cases of mediastinal lymphoma confirmed by pathology.Results 37 cases appeared as mediastinal masses,in which 25 cases were cross-regional growth of the mediastinum,1 1 cases in anterior mediastinum and 1 case in posterior mediastinum.The largest cross-sectional area of tumors was 1.6-129.6 cm^2 ,in which there were 1 case （0-10）cm^2 ,8 cases （10-25）cm^2 ,10 cases （25-50）cm^2 ,1 5 cases（50-100）cm^2 and 3 cases〉100 cm^2 .24 cases had necrosis ,among which 23 cases were slight enhanced and 1 case was seriously enhanced.Necrosis of mediastinal lymphoma was related to the size and CT enhancement of tumor by the logistic regression analysis（P 〈0.05）.Conclusion Mediastinal lymphoma with necrosis is common .The necrosis of mediastinal lymphoma is related to the size and CT enhancement.Slight CT enhancement is one of differential points between mediastinal lymphoma with necrosis and other mediastinal tumor.

关 键 词：纵隔 淋巴瘤 坏死 计算机体层成像 

分 类 号：R734.5[医药卫生—肿瘤] R814.42[医药卫生—临床医学]