腹水超滤浓缩回输腹腔术对肝硬化顽固性大量腹水并发Ⅱ型肝肾综合征的疗效探讨  

Clinical studies of ultafiltration reinfusion of concentrated ascites for the treatment of refractory ascites in liver cirrhosis with typeⅡhepatorenal syndrome

作　　者：伍欢[1] 刘亿军 

机构地区：[1]自贡市第一人民医院,四川自贡643000

出　　处：《临床消化病杂志》2014年第4期224-227,共4页Chinese Journal of Clinical Gastroenterology

摘　　要：[目的]探讨腹水超滤浓缩回输腹腔术对肝硬化顽固性大量腹水患者并发Ⅱ型肝肾综合征的疗效。[方法]将66例肝硬化顽固性大量腹水同时并发Ⅱ型肝肾综合征的患者随机分为治疗组(34例)和对照组(32例);治疗组采用腹水超滤浓缩回输腹腔术治疗,对照组采用腹腔穿刺放液治疗。[结果]2组治疗后,在改善24h尿量、降低血清尿素氮、降低血清K+方面均较治疗前有效,但治疗组明显优于对照组(P<0.05);2组不良反应发生率比较差异无统计学意义(P>0.05)。[结论]合理应用腹水超滤浓缩回输腹腔术是一种治疗肝硬化顽固性大量腹水并发Ⅱ肝肾综合征的有效措施,可迅速改善患者肾脏功能,明显增加尿量,缓解氮质血症,解除高钾血症。[Objective]To explore the effective treatment of refractory ascites in liver cirrhosis with type Ⅱ hepatorenal syndrome.[Methods]Sixty-six case of refractory ascites in liver cirrhosis with type Ⅱ hepatorenal syndrome patients were randomly divided into the treatment group（n=34）and the control group （n=32）.The control group received abdominal paracentesis apocenosis,the treatment group received ultrafiltration reinfusion treatment of concentrated ascites.[Results]The 24 h urinary volume in both groups was significantly increased and the serum urea nitrogen and hyperlipidemia after treatment was significantly dereased.The treatment group was significantly superior than the control group （P ＜ 0.05）.The difference was not significant in the incidence of adverse reaction（P＞0.05）.[Conclusion]Ultafiltration reinfusion of concentrated ascites is an effective treatment of refractory ascites in liver cirrhosis with type Ⅱ hepatorenal syndrome,which can rapidly improve renal function,increased urinary volume,decrease azotemia and hyperkalemia,to save the lives of patients.

关 键 词：肝硬化 顽固性腹水 肝肾综合征 腹水超滤浓缩回输腹腔术 

分 类 号：R575.2[医药卫生—消化系统]