小肝癌射频消融治疗后早期MR表现  

MRI early performance of primary SHCC after treatment by radiofrequency ablation

作　　者：曲蕾[1] 陈晓飞[1] 王淑艳[2] 陈立光[1] 袁振国[1] 赵斌[1] 

机构地区：[1]山东大学山东省医学影像学研究所,山东济南250021 [2]泰山医学院,山东泰安271000

出　　处：《医学影像学杂志》2014年第8期1327-1329,共3页Journal of Medical Imaging

基　　金：山东省自然基金(编号:2013ZRB14309);山东省科技攻关(政策引导类)项目(编号:2012YD18061);山东省医药卫生计划项目(编号:2011HW067);山东省科技攻关项目(编号:2008GG30002004)

摘　　要：目的探讨磁共振平扫和动态强化扫描在评估小肝癌射频消融(radiofrequency ablation,RFA)治疗后疗效的价值。方法 63例小原发性肝细胞癌75个肿瘤病灶射频消融前、后行48h内MRI常规、动态增强扫描并观察各序列信号变化。结果完全消融73个,48h内在GRE-T1WI射频消融区域全表现为高信号,TSE-T2WI及TSE-T2WI抑脂像表现为相对低信号,增强后早期射频消融区域主要表现为环状强化。2个伴残存癌细胞,表现为伴边缘小结节状小GRE-T1WI略低信号、SE-T2WI稍高信号并伴有中等度或明显动脉期强化。结论常规MRI扫描,联合动态强化对评价小肝细胞癌消融治疗的疗效及检测肿瘤残存具有重要作用,可成为早期随访的可靠方法。Objective To investigate the feasibility of magnetic resonance imaging （MRI） to assess the early effectivity after the treatment of radiofrequency ablation （RFA） for small primary hepatocellular carcinoma （SHCC）. Methods 75 lesions of small primary hepatocellular carcinoma （SHCC） in 63 cases were examinated in routine and dynamic enhancement MRI before and within 48 h after treatment of radiofrequency ablation, and the changes of sequence signal were observed. Results Seventy three RFA areas of 63 patients typically exhibited hyperintensity on T1WI and hypointensity on T2 WI within 48 h after ablation. On contrast, in enhanced MR images, RFA lesions were shown peripheral rim of enhancement within 48 h. The two residual tumor nodular lesions were found at the periphery of the RFA. These nodular lesions were shown moderate to marked enhancement as well as hypointense signal on T1WI, and moderate hyperintense signal on T2 WI. Conclusion Routine MRI may be one of imaging methods for effectively assessing the early effect of RFA on SHHC treated by RFA. Routine plain MRI combined with contrast enhanced MRI may improve the cucuracy of recurrence in SHCC after RFA treatment.

关 键 词：射频消融 磁共振成像 原发性肝细胞小肝癌 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]