添加纳米聚磷腈对聚氨酯材料微生物黏附性能的影响  

The effect of additional polyphosphazene nanotubes in polyurethane composites on microorganisms adhesion

作　　者：孔方圆[1] 郑元俐[2] 李静[2] 

机构地区：[1]上海交通大学医学院附属第九人民医院·口腔医学院牙体牙髓病科 [2]上海交通大学医学院附属第九人民医院·口腔医学院口腔修复科,上海市口腔医学重点实验室,上海200011

出　　处：《上海口腔医学》2014年第4期419-422,共4页Shanghai Journal of Stomatology

基　　金：上海市科学技术委员会资助项目(0941195470)~~

摘　　要：目的:观察纯聚氨酯材料(PU)、含1%和5%纳米聚磷腈的聚氨酯材料(PZS-1%、PZS-5%)表面白念菌和变形链球菌黏附情况。方法:测定3种材料(PU、PZS-1%、PZS-5%)表面粗糙度,并将其分别于白念菌和变链球菌菌液中进行黏附实验,分析材料表面微生物的黏附情况。采用SAS8.02软件包对数据进行统计学分析。结果:PU、PZS-1%和PZS-5%材料的表面粗糙度由大到小依次为PU>PZS-1%>PZS-5%(P<0.001);白念菌和变链球菌黏附实验中,黏附微生物量从多到少依次为PU>PZS-1%>PZS-5%(P<0.001)。结论:添加不同比例的纳米聚磷腈,对聚氨酯材料微生物黏附性能有一定影响。PUPPOSE： To investigate Candida albicans and Streptococcus mutans adhesion to 3 polyurethane composites[pure polyurethane（PU）, 1% polyphosphazene-containing polyurethane（PZS-1%） and 5% polyphosphazene-containing polyurethane（PZS-5%）]. METHODS： Two kinds of microorganism suspension were incubated with the specimens under certain culture conditions and the roughness of 3 materials were determined before adhesion tests. Microorganism attached to the specimen were then observed under optical microscope, and viable micro-organisms adhered to the specimen were then counted and removed. The data was analyzed with SAS 8.02 softwaree package. RESULTS： PU has the roughest surface followed by PZS-1% and PZS-5%. Most amounts of cell adhesion were observed in PU followed by PZS-1% and least amounts were found in PZS-5%. CONCLLUSIONS： The increase of polyphosphazene nanotubes in polyurethane composites may have an effect on cell adhesion. Surface roughness of the materials may be one of the factors.

关 键 词：聚氨酯 聚磷腈 白念菌 变形链球菌 

分 类 号：R783.1[医药卫生—口腔医学]