经导管肝动脉α-氰基丙烯酸正丁酯胶栓塞治疗肝内出血  

Transcatheter hepatic artery embolization with N-butyl cyanoacrylate in treatment of hepatic arterial bleeding

作　　者：谢坪[1] 李刚[1] 程美雄[1] 张天[1] 

机构地区：[1]四川省医学科学院四川省人民医院放射科,四川成都610072

出　　处：《中国介入影像与治疗学》2014年第9期569-572,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的探讨以α-氰基丙烯酸正丁酯胶(NBCA)作为栓塞剂经导管肝动脉栓塞治疗肝内出血的价值。方法收集接受经导管肝动脉栓塞治疗的肝动脉出血患者7例,均使用NBCA作为栓塞剂,评价技术成功率、临床有效率及相关并发症。结果造影显示假性动脉瘤6例,对比剂外溢1例。对7例患者均成功施行经导管肝动脉栓塞术,术后即刻造影假性动脉瘤和对比剂外溢征象消失,技术成功率100%;NBCA及超液化碘油混合剂用量为(0.76±0.24)ml;术后患者腹痛症状缓解,血红蛋白浓度升高,临床有效率100%。未发生手术相关并发症,随访1个月无再出血病例。结论采用NBCA胶行经导管肝动脉栓塞治疗肝内出血安全有效,具有重要临床应用价值。Objective To explore the value of transeatheter hepatic artery embolization with N-butyl cyanoacrylate （NB- CA） in treatment of hepatic artery bleeding. Methods Transeatheter hepatic artery embolization was performed in 7 patients with hepatic arterial bleeding taken NBCA as embolic agent. The technical success rate, clinical effective rate and procedure-related complications were evaluated. Results Angiography showed pseudoaneurysm in 6 cases and extravasation of contrast in 1 case. Hepatic artery embolization was successfully performed in all the 7 patients with the mixture of NBCA and lipiodol of （0.76±0.24）ml. Immediately after embolization, the sign of pseudoaneurysm and extravasation of contrast disappeared, and the technical success rate was 100%. After embolization, bellyache relieved, and hemoglobin level increased, clinical effective rate was of 100;. No serious complications related to embolization procedure occurred, while no recurrent bleeding was observed during 1 month following-up. Conclusion Transcatheter hepatic artery embolization with NBCA is safe and effective in treatment of hepatic bleeding, having important clinical application value.

关 键 词：出血 肝 α-氰基丙烯酸正丁酯胶 栓塞 治疗性 

分 类 号：R575[医药卫生—消化系统] R816.5[医药卫生—内科学] R445.2[医药卫生—临床医学]