乳腺癌新辅助化疗病人癌因性疲乏状况的研究  

Study of neoadjuvant chemotherapy of breast cancer patients' cancer- related fatigue status

作　　者：雷林瑜[1] 

机构地区：[1]郑州人民医院普通外科,郑州450003

出　　处：《医药论坛杂志》2014年第9期60-61,共2页Journal of Medical Forum

摘　　要：目的研究乳腺癌新辅助化疗后癌因性疲乏状况,为乳腺癌患者制定疗效好、副作用小的化疗方案提供参考依据。方法选取郑州人民医院普通外科2012年3月—9月确诊为乳腺癌且行FAC或TC方案化疗的患者进行研究,分别在实施化疗前及化疗第一、二、三个疗程后,使用修订的Piper疲乏量表(RPFS)评价分析用新辅助化疗方法后癌因性疲乏的发生状况进行统计分析。结果经过3次疗程后其RPFS量表评分中行为、情感、感受、情绪等方面均较治疗前增加,差异有统计学意义(P<0.01),在RPFS总分上也有明显的差异(P<0.01)。结论患者的癌因性疲乏的发生率和严重程度会随着化疗疗程的推移和时间的进展产生明显的差别。Objective To study the breast cancer after neoadjuvant chemotherapy cancer- related fatigue status and provide some effective and better references for breast cancer patients＇ chemotherapy. Methods Choose the patients of Zhengzhou People＇s Hospital General Surgery Dept. from March to September 2012 who were diagnosed with breast cancer. Application of FAC solutions or TC solutions to study,and chemotherapy before the chemotherapy respectively after1,2,3,using the revised Piper fatigue scale（RPFS） assessment and analysis with neoadjuvant chemotherapy method after cancer- related fatigue occurring condition were analyzed. Results After 3 period of treatment after the RPFS rating scale of behavior,emotions,feelings,emotions,etc was increased,the difference was statistically significant（ P〈0. 01）,also have obvious differences in RPFS scores（P〈0. 01）. Conclusion With the passage of chemotherapy regimen and the progress of time,the incidence of patients with cancer- related fatigue and severity is an obvious difference.

关 键 词：乳腺癌 新辅助化疗 癌因性疲乏 

分 类 号：R737.9[医药卫生—肿瘤]