白内障患者血清、房水及泪液中IL-2,sIL-2,NO,TAC及SOD的变化研究  

Study on the change of serum,aqueous humor and tear IL-2,sIL-2,NO,TAC,and SOD of patients with cataract

作　　者：沈惠芳 谢欣[2] 

机构地区：[1]中国浙江省德清县第三人民医院眼科,313201 [2]浙江大学医学院附属二医院眼科中心,中国浙江省杭州市310009

出　　处：《国际眼科杂志》2014年第9期1635-1637,共3页International Eye Science

摘　　要：目的:研究及观察白内障患者血清、房水及泪液IL-2,sIL-2,NO,TAC及SOD的变化情况。方法:选取2011-11/2013-09本院收治的60例白内障患者为观察组,并以同期的60例眼外伤患者为对照组,将两组的血清、房水及泪液IL-2,sIL-2,NO,TAC及SOD水平进行检测与比较,并比较不同白内障分期者的检测水平。结果:观察组的血清、房水及泪液IL-2,TAC及SOD水平均低于对照组,而sIL-2及NO水平则均高于对照组,且不同分期者的血清、房水及泪液检测水平也存在明显差异,其中房水的IL-2低于血清及泪液,sIL-2则高于血清及泪液,均有显著性差异。结论:白内障患者的血清、房水及泪液IL-2,sIL-2,NO,TAC及SOD的变化均较大,并且受分期影响较大,并且房水中的炎性反应状态更为明显。AIM： To study and observe the changes of serum,aqueous humor and tear IL-2,sIL-2,NO,TAC,and SOD of patients with cataract.METHODS： Totally 60 patients with cataract in our hospital from November 2011 to September 2013 were included as the observation group,and 60 patients with eye traumas were as the control group. The serum,aqueous humor and tear IL-2,sIL-2,NO,TAC,and SOD of two groups were detected and compared, and the detection levels of patients with different stages were compared.RESULTS： The serum,aqueous humor and tear IL-2,TAC,and SOD of observation group were all lower than those of control group,the sIL-2 and NO were all higher than those of control group. The serum,aqueous humor and tear detection levels of patients at different stages had obvious differences,and the aqueous humor IL- 2 were lower than those of serum and tear,the sIL-2 were higher than those of serum and tear,with statistically significantdifferences.CONCLUSION： The change of serum,aqueous humor and tear IL-2,sIL-2,NO,TAC,and SOD of patients are all great,and the influence of the stages for those indexes are great too,the inflammatory response state of aqueous humor are more obvious.

关 键 词：白内障 血清 泪液 IL-2 SIL-2 NO TAC SOD 

分 类 号：R776.1[医药卫生—眼科]