短暂性脑缺血发作与颈动脉粥样硬化及其他因素的关系  

Relationship between transient ischemic attack and carotid atherosclerosis or other factors

作　　者：王振凤[1] 朱长东[1] 韩家裕 胡成[1] 

机构地区：[1]赣南医学院第二附属医院内科,江西赣州341600

出　　处：《中国现代医药杂志》2014年第9期13-15,共3页Modern Medicine Journal of China

摘　　要：目的 探讨短暂性脑缺血发作（TIA）与颈动脉粥样硬化及其他影响因素间的关系。方法 选择2010年6月-2013年6月我院神经内科收治的TIA患者60例为观察组,另选取同期健康体检者40例作为对照组,对两组间的相关生化指标检测及颈动脉彩色多普勒超声检查结果进行对比分析。结果 观察组中吸烟、高血压、高血糖、肥胖、高脂血症、糖尿病的发生率均高于对照组,差异具有统计学意义（P〈0.05）;观察组患者的TC、LDL、FBG及Hcy均高于对照组,HDL含量低于对照组,差异具有统计学意义（P〈0.05）,两组TG含量相比无显著性差异（P〉0.05）;观察组共41例检测出易损斑块,检出率为68.3%;对照组共7例检测出易损斑块,检出率为17.5%,两组比较差异具有统计学意义（P〈0.05）。结论 颈动脉粥样硬化斑块与TIA的发生密切相关,预防颈动脉粥样硬化斑块的发生能有效降低TIA的发病率,全面评估颈动脉粥样硬化斑块对于TIA的早期诊断和预后预测有非常重要的意义。Objective To investigate the relationship between transient ischemic attack and carotid atherosclerosis or other factors. Methods 60 cases of TIA patients treated in our hospital from Jun 2010 to Jun 2013 were selected as observation group, concurrently with 40 health persons as control group. Compared the results of biochemical indexes detection and ＂the carotid color Doppler ultrasonography between the two groups. Results The incidence of smoking, hypertension, hyperglycemia, obesity, hyperlipidemia and diabetes mellitus in observation group were higher than those of control group, the differences were statistically significant （P〈0.05）, the TC, LDL, FBG and Hcy of patients in observation group were higher than those of control group, the differences were statistically significant （P〈0.05）, HDL content of patients in observation group was lower than that of control group, the difference was significant （P〈0.05）, there was no significant difference in the content of TG between the two groups （P〉0.05）. Vulnerable plaque was detected in 41 cases and 7 cases with a detection rate of 68.3% and 17.5% in observation group and control group respectively, the difference was statistically significant （P〈0.05）. Conclusion Carotid atheroosclerotic plaque is closely related to TIA. Preventing the occurrence of carotid atherosclerotic plaque can effectively reduce the incidence of TIA. Comprehensive evaluation on carotid atherosclerosis plaque is important for the early diagnosis and prognosis prediction of TIA.

关 键 词：短暂性脑缺血发作 颈动脉粥样硬化 相关因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]