克罗恩病微生态学变化及其对临床应用的启示  

Change in characteristics of intestinal microbiota and its enlightenment for clinical management of Crohn's disease

作　　者：陈立平[1] 夏冰[1] 

机构地区：[1]武汉大学中南医院消化内科湖北省肠病医学l临床研究中心肠病湖北省重点实验室,武汉430071

出　　处：《中国实用内科杂志》2014年第9期871-874,共4页Chinese Journal of Practical Internal Medicine

基　　金：国家自然科学基金(81070280,81270467)

摘　　要：无论是在疾病的诊断和治疗,还是在复发的预测与干预方面,克罗恩病依然是一个困扰临床的难题。对肠道微生态的研究为我们破解这个难题提供了新的思路。初步的研究提示,克罗恩病患者特征性的肠道菌群改变在疾病的诊断、治疗以及复发的判断等方面显示出潜在的应用价值。可以预见,随着研究的深入,肠道微生态在克罗恩病的临床应用中将发挥更重要的作用。Crohn＇s disease （CD） remains a difficult clinical problem for us either in the diagnosis and treatment or in the prediction and prevention of recurrence. However, it provides us a new perspective to deal with CD to study the intestinal mi- crobiota of patients with CD. Preliminary studies suggest that the characteristic changes of intestinal microbiota in patients with CD showed us the potential value in the diagnosis, treatment and prediction of recurrence in CD. It can be foreseen that with further study intestinal microbiota will play a more important role in clinical management of CD.

关 键 词：肠道微生态 克罗恩病 

分 类 号：R574[医药卫生—消化系统]