恶性肿瘤的^(90)Y-玻璃微球瘤内注射治疗及其临床效果观察  

Clinical Observation of Malignant Tumors Treated with Intervention of ^(90)Y-Glass Microspheres

作　　者：朱慧[1] 李佳丽[1] 朱卫[1] 牛静秀[1] 应简子[1] 庞雁[1] 

机构地区：[1]天津市人民医院肿瘤科,天津300121

出　　处：《标记免疫分析与临床》2014年第4期364-366,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨90Y-玻璃微球介入治疗晚期恶性肿瘤的疗效。方法共18例恶性肿瘤病人,其中肝癌6例,肺癌5例,颈部淋巴结转移癌5例,上颌窦癌1例,肺癌胸壁转移1例,均经病理诊断证实。采取直接注入或者利用B超和CT引导下将90Y-玻璃微球引入肿瘤组织。结果 18例肿瘤中,完全消失(CR)为2例,部分缩小(PR)为9例,肿瘤稳定(SD)为6例,肿瘤进展(PD)为1例。14例病人可见疼痛减轻,4例疼痛未见明显缓解。结论本方法可在晚期恶性肿瘤治疗上发挥重要作用,有较大临床应用前景。Objective To explore the therapeutic effect of malignant cancer treated with intervention of 90Y lasbelled glass mierospheres. Methods 18 cancer patients with primary tumor located in liver （6 cases） , lung （5 cases）, cervical lymph node metastases （5 cases ）, maxillary sinus carcinoma （1 case ） and chest wall metastasis （1 case） were included in the study. All patients were confirmed by pathological diagnosis. 90Y lasbelled glass microspheres was injected with or without the help of type-B ultrasonic and CT. Results Out of 18 cases of patients,2 cases were CR,9 cases were PR,6 cases were SD and one case was PD. 14 cases were showed pain relief and the other 4 cases were no significant relief of pain. Conclusion This method is effective in the therapy of malignant cancer, and it has great potential for clinical application.

关 键 词：恶性肿瘤 90Y 玻璃微球 瘤内注射 

分 类 号：R730.5[医药卫生—肿瘤]