^(13)C-尿素呼气试验检测胃幽门螺杆菌感染2275例报告  

Detection of Gastric Helicobacter Pylori Infection by ^(13)C-urea Breath Test

作　　者：叶科学 高鑫[1] 李淑湘[1] 朱耿超[1] 汪宪平[1] 

机构地区：[1]南京医科大学附属苏州医院核医学科,江苏苏州215002

出　　处：《标记免疫分析与临床》2014年第4期375-377,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的了解全年龄段有消化道症状患者的幽门螺杆菌(Hp)感染情况。方法选取本院门诊及住院有慢性上腹疼痛、反复上消化道出血等消化道症状的患者共2275例,年龄2~88岁,男1058例,女1217例。采用13C-尿素呼气试验的检测方法,分析幽门螺杆菌感染的检测结果。结果 2275例患者中,13C-尿素呼气试验阳性者928例,占40.79%。男性患者,阳性414例,占39.13%;女性患者,阳性514例,占42.23%,女性高于男性(P<0.01)。各全年龄段中,以31~45岁年龄组幽门螺杆菌感染率为最高,阳性333例,占48.40%。成人各年龄段与15岁以下年龄组相比,HP感染率差异有统计学意义(P<0.01)。结论对31~45岁年龄段的人群应给予关注,同时应通过健康教育提高人们的相关知识水平,有针对性地开展Hp筛查,早诊断、早治疗,从而有效预防和控制胃部疾病的发生。Objective To explore the situation of Helicobacter Pylori infection in the all age group of patients with gastrointestinal symptoms. Methods A total of 2275 outpatients and inpatients in our hospital with the gastrointestinal symptoms including chronic upper abdominal pain and hemorrhage were collected. 1058 males and 1217 females, aged from 2 to 88 years old （mean 40.25 ± 19.79） were received 13C-Urea breath test （13C-UBT）in Suzhou Municipal Hospital. The 13C-UBT results were analyzed to detect the incidence of helicobacter pylori infection. Results According to the results of 13C -UBT test,40.77% were HP positive in all these 2275 patients,while 39.13% were positive in the 1058 male eases,42.23% were positive in the 1217 female cases. The 13C-UBT levels were significantly higher in females than that of males （P 〈 0.01 ）. Among all age groups, patients at 31 -45 years old group had highest rate of HP infection （48.40%）. Compare to under 15 years old group, adults group have higher rate of HP infection （ P 〈 0.01 ）. Conclusion Patients at 31 -45 years old group have highest rate of HP infection. It is necessary for us to focus on these patients. Education should be strengthened in order to increase people＇ s knowledge of HP infection. Early diagnosis and treatment will effectively prevent and control the gastrointestinal disease.

关 键 词：13C-尿素呼气试验 幽门螺杆菌 

分 类 号：R573[医药卫生—消化系统]