复方托吡卡胺和硫酸阿托品在儿童散瞳验光中的效果评价  

Application of compound tropicamide and atropine in mydriatic refractometry for ametropia children

作　　者：吴艳[1] 丁莉莉[2] 杨丽萍[1] 曹茜[1] 

机构地区：[1]南京军区南京总医院眼科,南京210002 [2]南京军区南京总医院干部保健科,南京210002

出　　处：《实用药物与临床》2014年第9期1203-1205,共3页Practical Pharmacy and Clinical Remedies

基　　金：国家自然科学基金面上项目资助(30670600)

摘　　要：目的 评价复方托吡卡胺和硫酸阿托品在儿童散瞳验光中的效果.方法 随机抽取屈光不正儿童126例（252眼）,年龄4 ～18岁,按年龄分为A组（＜8岁）40例（近视22例,远视18例）、B组（8～12岁）48例（近视33例,远视15例）、C组（＞12岁）38例（近视21例,远视17例）.所有患儿先后使用复方托吡卡胺眼液和阿托品凝胶散瞳后行电脑验光并记录屈光度.用配对t检验分析其统计学意义.结果 复方托吡卡胺眼液和阿托品眼凝胶对儿童远视屈光不正散瞳后,A、B组患者所得的屈光度值比较差异有统计学意义（P＜0.05）,C组差异无统计学意义（P＞0.05）;对儿童近视屈光不正散瞳后,A组患者使用2种散瞳方法所得的屈光度值比较差异有统计学意义（P＜0.05）,B、C组差异无统计学意义（P＞0.05）.结论 阿托品散瞳验光对8岁以下近视患儿和12岁以下远视患儿的验光是必要的.Objective To compare the effect of compound tropicamide and atropine ophthalmic solution in mydriatic refractometry for ametropia children.Methods 126 cases （252 eyes） arnetropia children aged from 4 to 18 years were randomly selected,using two kinds of mydriatic （compound tropicamide and atropine）to dilate the pupils successively.All cases were grouped by age as group A（＜8 years）,group B（8 ～ 12 years）and group C（＞ 12 years）.The optometry results were measured and compared by paired T-test.Results There was significant difference in diop ter of hypermetropia children in group A and group B （P ＜ 0.05）between different mydriatic drugs treatment,while no significant difference was found in group C （P ＞ 0.05）.There was significant difference was found in group A （P ＜0.05）for myopia children,while no significant difference was found in group B and group C（P ＞ 0.05）.Conclusion The application of atropine in mydriatic refractometry for myopia children aged below 8 years and hypermetropia chil dren aged below 12 years is necessary.

关 键 词：复方托吡卡胺 阿托品 散瞳验光 屈光不正 

分 类 号：R778.13[医药卫生—眼科]