31例白血病患者肺弥散功能检查的对照研究  

Control study on lung diffusing capacity of 31 leukemia patients

作　　者：赖莉芬[1] 韩志海[1] 周怡[2] 刘方[1] 舒六一[1] 张春阳[1] 

机构地区：[1]海军总医院呼吸内科,北京100048 [2]解放军309医院呼吸内科,北京100091

出　　处：《临床肺科杂志》2014年第10期1761-1763,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察分析白血病患者的肺弥散功能变化。方法对31例肺通气功能正常的白血病患者进行肺弥散功能测定,同时选择30例外科术前患者作为对照组。分别获得两组未用血红蛋白(Hb)校正的弥散量DLCO、DLCO实测值/预计值(A/P)及Hb校正后的DLCO(DLCOAdj)、DLCOAdj(A/P)。结果对照组DLCO与DLCOAdj、DLCO(A/P)与DLCOAdj(A/P)无统计学意义(P>0.05);白血病组DLCO与DLCOAdj、DLCO(A/P)与DLCOAdj(A/P)有统计学意义(P<0.05);两组间DLCO、DLCOAdj、DLCO(A/P)、DLCOAdj(A/P)有统计学意义(P<0.05)。结论白血病患者肺弥散功能有不同程度降低,临床分析肺弥散功能异常的原因时,首先应排除Hb的影响因素,再结合肺CT和临床资料分析其它影响因素。Objective To observe the changes of lung diffusing capacity of leukemia patients. Methods The changes of lung diffusing capacity of 31 leukemia patients were tested by German CareFusion spirometer,and 30 surgical patients before operation were taken as controls. DLCO DLCO（ A /P） without Hb adjustment and DLCOAdj DLCOAdj（ A /P） with Hb adjustment were recorded. The data were analyzed by CHISS software. Results There was no statistical significance in DLCO vs. DLCOAdj,DLCO（ A /P） vs. DLCOAdj（ A /P） in the control group,but there were significant differences in the study group（ P〈0. 05） and between the two groups（ P〈0. 05）.Conclusion There are different degree decreases in DLCO of leukemia patients. While clinically analyzing the causes of DLCO disorder,the Hb factor should be excluded first,and other factors are investigated thereafter based on lung CT scan and clinical data.

关 键 词：白血病 血红蛋白 校正 弥散功能 

分 类 号：R733.7[医药卫生—肿瘤]