强化干预代谢综合征改变心脑血管事件发病率的临床探讨  

Clinical Study of Intensive Intervention to Change the Metabolic Syndrome Incidence of Cardiovascular and Cerebrovascular Events in

作　　者：黄雯 李伟荣 莫发敏 

机构地区：[1]佛山市三水区人民医院,广东佛山528100

出　　处：《中国医药指南》2014年第25期50-52,共3页Guide of China Medicine

摘　　要：目的探讨改变代谢综合征患者心脑血管事件发病率的强化干预措施,并比较分析干预效果。方法以2011年5月至8月在我院体检中心进行健康体检的三水区事业单位职工3480例作为研究对象,强化干预组共1740例,其中MS组286例,非MS组1454例;对照组共1740例,其中MS组305例,非MS组1435例。对照组接受自主常规的临床治疗;强化干预组接受常规治疗的同时,根据患者是否患有代谢综合征及其相关疾病、疾病前状态(包括高血压、肥胖、超重、糖尿病、糖耐量减退、血脂异常)等分别采取不同的强化治疗方案进行干预。分别统计两组患者在治疗前后体质量指数、血压、血脂、空腹血糖等指标变化和心脑血管事件发生情况。结果强化干预组MS亚组患者治疗后血压下降(9.53±2.43)mm Hg(1 mm Hg=0.133 kPa),空腹血糖为(6.26±1.17)mmol/L,对照组MS亚组患者分别为(5.61±2.65)mm Hg和(6.89±1.19)mmol/L,强化干预组改善效果明显优于对照组,具有统计学意义(P<0.05)。强化干预组中,MS亚组患者的冠心病事件和脑卒中事件的发生数分别为28例和26例,而非MS亚组患者的冠心病事件和脑卒中事件的发生数分别为99例和91例;对照组中,MS亚组患者的冠心病事件和脑卒中事件的发生率分别为40例和41例,而非MS亚组患者的冠心病事件和脑卒中事件的发生率分别为172例和174例。强化干预组MS亚组心脑血管事件的发生例数,明显低于对照组MS亚组患者的发生例数,强化干预组非MS亚组的患者例数明显低于对照组非MS亚组的患者例数,组间对比均具有统计学意义(P<0.05)。结论强化干预手段联合治疗代谢综合征患者,可以有效降低心脑血管事件的发病率,值得临床积极推广。Objective To investigate the metabolic changes of comprehensive strengthen intervention measures in patients with cardiovascular and cerebrovascular morbidity, and comparative analysis of intervention effect. Methods Sanshui District institution staff to 2011 from May to August in our hospital medical center for health examination in 3480 cases as the research object, the intervention group were 1740 cases, including 286 cases of MS group, non MS group 1454 cases; the control group of 1740 cases, including 305 cases of MS group, non MS group of 1435 cases. The control group received conventional treatment independently; the intervention group received conventional treatment at the same time, according to whether patients with metabolic syndrome and its related diseases, disease state（including hypertension, obesity, overweight, diabetes, impaired glucose tolerance, dyslipidemia） divided different strengthening intervention. Compared between the two groups before and after treatment in patients with body mass index, blood pressure, blood lipid, fasting blood glucose and other indicators of changes in cardiac and cerebrovascular events. Results Strengthening intervention group MS sub group patients after blood pressure decreased by（9.53±2.43）mm Hg, fasting blood sugar was（6.26±1.17）mmol/L, control group MS subgroups of patients were（5.61±2.65）mmHg and（6.89±1.19）mmol/L, the intervention group improved significantly better than the control group, with statistical significance（P〈0.05）. The intervention group, MS subgroups of patients with coronary heart disease and stroke were 28 cases and 26 cases, and non MS subgroups of patients with CHD events and stroke events were 99 cases and 91 cases; control group, the incidence of MS subgroups of patients with CHD events and stroke events there were 40 cases and 41 cases, rather than the incidence of MS subgroups of patients with CHD events and stroke events were 172 cases and 174 cases. Strengthening of the intervention group subgroup MS of car

关 键 词：代谢综合征患者 心脑血管事件发病率 强化干预 

分 类 号：R743[医药卫生—神经病学与精神病学]