HCCR蛋白的表达与HBsAg浓度的关系  

The Relationship of the Expression of HCCR with the Concentration of Serum HBsAg

作　　者：张华[1] 王新华[1] 周勇军[1] 

机构地区：[1]湖南省益阳市中心医院检验科,湖南益阳413000

出　　处：《中国医药指南》2014年第26期34-35,共2页Guide of China Medicine

摘　　要：目的探讨血清乙型肝炎病毒表面抗原浓度与人宫颈癌基因蛋白及甲胎蛋白的相关性。方法收集100例健康体检者和400例HBsAg阳性患者的血清,根据HBsAg浓度分为A、B、C、D四组。采用ELISA检测HCCR和HBsAg,化学发光法检测AFP。结果不同HBsAg浓度组与对照组HCCR、AFP比较,差异均有统计学意义(P<0.05);HBsAg浓度越高,血清中HCCR、AFP水平越高,且HCCR与AFP成正相关。结论随着HBsAg浓度的升高,血清中HCCR与AFP水平逐渐增高,且HCCR与AFP成正相关。Objective To explore the correlation between the concentration of serum HBsAg,HCCR and AFP. Methods Serum samples of 400 cases patients with HBsAg and 100 cases healthy people were collected. According to the concentration of HBsAg, the serum samples were assigned into four groups. Enzyme-linked immuno sorbent assay was used to detect HCCR and HBsAg. Chemoluminescence was used to detect AFP. Results When HCCR and AFP in the groups of different concentration of serum HBsAg were compared with those in the control group, their levels were different significantly （P〈0.05）. The levels of serum HCCR and AFP increased gradually with the increase of the concentration of HBsAg and the level of HCCR was positively correlated with the level of AFP （P〈0.01）. Conclusions The levels of serum HCCR and AFP increased gradually with the increase of the concentration of HBsAg and the level of HCCR was positively correlated with the level of AFP.

关 键 词：人宫颈癌基因 甲胎蛋白 

分 类 号：R737.33[医药卫生—肿瘤] R446[医药卫生—临床医学]