PP放疗增敏放化疗同步与放化疗序贯治疗复发耐药肿瘤疗效的比较分析  

Comparative Analysis of PP Radiosensitization Chemotherapy and Chemoradiotherapy Synchronous Sequential Treatment of Recurrent Tumor Efficacy of Drug-resistant

作　　者：黄喜锋 

机构地区：[1]荆门市中医医院,湖北荆门448000

出　　处：《中国医药指南》2014年第27期56-57,共2页Guide of China Medicine

摘　　要：目的探究不同方法治疗复发耐药肿瘤的临床疗效,分析不同方法的优点。方法选择在本院初次治疗或者转诊到本院的80例耐药肿瘤复发病例,按患者自愿将其分成对照组41例患者和试验组39例患者,试验组患者采用PP放疗增敏放化疗同步进行治疗,对照组选用放化疗序贯治疗对复发肿瘤进行治疗。近期治疗效果监测指标包括:RR(有效率),稳定间期,不良反应等;及远期疗效。结果试验组与对照组相比有效率明显提高,延长稳定期间(P<0.05)。不良反应不变或减轻。远期疗效两组没有差异(P>0.05)。结论 PP放疗增敏放化疗同步法治疗复发进展期肿瘤临床总体疗效优于放化疗序贯组治疗,不良反应相对较轻,而且实践操作难度低。Objective To explore the clinical effect of different methods of treatment of recurrent tumor, the analysis of advantages of different methods. Methods In the initial treatment or referral to 80 cases of tumor recurrence in our hospital, according to the patient＆#39;s voluntary divided into a control group of 41 patients and 39 patients in the test group, the test group were treated by PP radiation sensitizing radiotherapy and chemotherapy treatment, the control group used chemotherapy sequential therapy for the treatment of tumor recurrence. Including the recent therapeutic effect monitoring indexes： RR （efficiency）, stable interval, curative effect and long-term adverse reaction. Results In the experimental group compared with the control group were markedly improved the efficiency, prolong the stability period（P〈0.05）. Adverse reaction of unchanged or reduced. Long term effect of the two groups had no difference（P〉0.05）. Conclusion PP radiotherapy concurrent chemotherapy treatment of recurrent advanced tumor clinical overall efficacy than chemotherapy sequential therapy group, adverse reactions are relatively mild, but in practice the operation difficulty is low.

关 键 词：同步放化疗 序贯放化疗 复发肿瘤 耐药肿瘤 

分 类 号：R730.5[医药卫生—肿瘤]