超声波联合疏血通治疗短暂性脑缺血发作的效果  

Results of ultrasound combined with Shuxuetong in treating transient ischemic attack

作　　者：郝树森[1] 张丽英[1] 高连生[1] 康红霞[1] 杨晓玲[1] 李军[1] 常宁[1] 綦航 

机构地区：[1]河北省石家庄市第八医院内科,河北石家庄050081

出　　处：《中国医药导报》2014年第29期28-30,34,共4页China Medical Herald

基　　金：河北省科学技术研究与发展计划项目(编号122777114)

摘　　要：目的 探讨体外超声波联合疏血通治疗短暂性脑缺血发作的临床效果及观察治疗前后血浆溶血磷脂酸极性相似总磷脂（AP）、椎动脉峰时的改变。方法 选择2012年10月～2013年2月河北省石家庄市第八医院内科收治的短暂性脑缺血发作患者110例为研究对象,根据治疗方法不同将其分为联合治疗组（n=60）和对照组（n=50）。两组均给予疏血通6 mL加入0.9%氯化钠250 mL静脉滴注,每日1次,连用14 d,联合治疗组在对照组治疗的基础上加用体外（头部）超声波,每日2次,连用14 d。检测并比较两组治疗前后AP、椎动脉峰时及疗效。结果治疗后,联合治疗组和对照组AP[（3.82±0.80）、（4.25±0.54）U]及椎动脉峰时[（0.126±0.009）、（0.133±0.012）s]较治疗前[AP：（6.43±1.52）、（6.26±1.52）U;椎动脉峰时：（0.162±0.013）、（0.164±0.013）s]显著降低,差异均有统计学意义（P〈0.05）,治疗后联合治疗组患者AP和椎动脉峰时均明显低于对照组,差异均有统计学意义（P〈0.05）。联合治疗组总有效率（98.3%）显著高于对照组（74.0%）,差异有高度统计学意义（P〈0.01）。结论 体外超声波联合疏血通治疗短暂性脑缺血发作有很好的效果。Objective To investigate the clinical efficacy of ultrasound combined with Shuxuetong in treating transient ischemic attack and the change of plasma lysophosphatidic acid polarity similar total phospholipids （AP）, the peak time of the vertebral artery before and after treatment. Methods 110 cases of patients with transient ischemic attack from October 2012 to February 2013 in the Eighth Hospital of Shijiazhuang were selected as study objects, and they were di- vided into combination treatment group （n = 60） and control group （n = 50）; the patients in two groups were given Shuxuetong 6 mL in 0.9% sodium chloride 250 mL, 1 time per day, for 14 days; combination treatment group were giv- en the vitro （head） ultrasound treatment in addition, 2 times per day, for 14 days. AP and vertebral artery peak time before and after treatment were detected and compared, the efficacy of two groups were observed and compared. Re- suits After treatment, the AP and vertebral artery peak of the combination treatment group and control group [AP： （3.82±0.80）, （4.25±0.54） U; vertebral artery peak time： （0.126±0.009）, （0.133±0.012） s] were significantly reduced, compared with pre-treatment lAP： （6.43±1.52）, （6.26±1.52） U; vertebral artery peak time： （0.162±0.013）, （0.164±0.013） s], the differences were statistically significant （P 〈 0.05）, while after treatment, AP and vertebral artery peak time of the combination treatment group were lower than those of the control group, the differences were statistically significant （P 〈 0.05）. The total efficiency of the combined treatment group （98.3%） was significantly higher than that of the con- trol group （74.0%）, the difference was statistically significant （P 〈 0.01）. Conclusion Ultrasound combined with Shuxu- etong in treating transient ischemic attacks have a good effect.

关 键 词：短暂性脑缺血发作 超声波 疏血通 总磷脂 椎动脉峰时 

分 类 号：R743.31[医药卫生—神经病学与精神病学]