膀胱内翻性乳头状瘤28例临床病理分析  

Clinical pathological analysis of inverted papilloma of the bladder of 28 cases

作　　者：张莉[1] 薛林[1] 何建春[1] 

机构地区：[1]攀钢集团总医院病理科,四川攀枝花617023

出　　处：《中国冶金工业医学杂志》2014年第5期505-506,共2页Chinese Medical Journal of Metallurgical industry

摘　　要：目的探讨膀胱内翻性乳头状瘤的临床病理特点、诊断及鉴别诊断。方法回顾我院28例膀胱内翻性乳头状瘤患者的临床资料,结合以往文献资料对膀胱内翻性乳头状瘤的临床特点进行分析,HE染色,光镜观察。结果肉眼观察：肿瘤直径0.5-6cm,平均2.4cm,呈息肉状,有蒂或广基,表面较光滑。镜下观察：28例膀胱内翻性乳头状瘤其基本组织学图像为表面被覆形态正常的移行上皮细胞,增生的上皮细胞向下凹陷呈内生性生长,形成上皮巢状结构,巢中心为平行排列的上皮细胞,周围细胞呈栅栏状排列。瘤细胞卵圆形或梭形,形态规则,大小一致,无异型性,偶见核分裂相。结论膀胱内翻性乳头状瘤是一种少见的预后好、复发少的良性肿瘤,确诊需排除尿路上皮癌、低度恶性潜能的乳头状瘤和腺性囊性膀胱炎。Objective To study the clinical pathological characteristics,the diagnosis and differential diagnosis of inverted papilloma of bladder （IPB）. Methods 28 cases of IPB in our hospital were reviewed combined with the previous literatures. The clinical characters, HE stains and microscope finding were analyzed. Results Macroscopic finding were that diameter of tumors be from 0. 5cm to 6 cm（average 2.4 cm） ,polypoid, pedunculated or wide base, smooth surface. The general histological images of microscopic were that the surface coating normal transitional epithelial cells, proliferation of epithelial cells being endogenous growth downward sunken, epithelial nest formation with parallel epithelial cells in nest center and palisading surrounding. Tumor cells were ovoid or fusiform, regular shape, consistent in size,without atypia and occasional mitotic phase. Conclusion IPB is a rare benign tumor with well prognosis and less relapse. We should eliminate urothelial carcinoma,potential of low-grade malignant inverted papilloma and cystitis glandularis cystica to confirm the diagnosis.

关 键 词：病理学 内翻性乳头状瘤 诊断 鉴别诊断 

分 类 号：R737.14[医药卫生—肿瘤]