Effects of sleep deprivation on polysomnography and executive function in patients with depression  

作　　者：Lu Yingzhi Ren Qingtao Zong Li Wu Yingli Zhang Qinfeng Ma Xiuqing Pu Jinyu Dong Hanzhen Liu Qingqing Tang Yunxiang Song Lisheng Chen Xingshi Pan Xiao Cui Yi 

机构地区：[1]Department of Psychiatry, Zibo Mental Health Center, Zibo,Shandong 255100, China [2]Zibo Occupational Disease Hospital of Prevention and Treatment, Zibo, Shandong 255067, China [3]Department of Medical Psychology, Faculty of Psychology andMental Health, Second Military Medical University, Shanghai200433, China [4]Department of Electrophysiology, Shanghai Mental Health Center,Shanghai Jiao Tong University, Shanghai 200030, China

出　　处：《Chinese Medical Journal》2014年第18期3229-3232,共4页中华医学杂志（英文版）

基　　金：This study was supported by the grants from the National Natural Science Foundation of China （No. 81271480 and No. 81372122）, the Emerging Advanced Technology Projects from Shanghai Hospital Development Center （SHDC 12013116）, and Projects of Promotion of Advanced Appropriate Technology in Health Service in Shanghai （No. 2013SY069）.

摘　　要：Anumber of therapies have been developed in the past decades.About two thirds of patients can be seizure free with antiepileptic drugs.1 Other patients are drug resistant,some of whom are good candidates for epileptic focus resection and become seizure free after surgery.2 The treatment for drug-resistant patients who are not eligible for resection is still challenging.Traditionally,these patients can receive palliative surgery such as callosotomy and multiple subpial transection,3,4 but the long-term outcomes of these procedures are not satisfactory.5-7 In the past decades,neuromodulation techniques have been applied in the treatment of epilepsy.Much evidence has been accumulated about the therapeutic effects of vagus nerve stimulation for epilepsy.In contrast to peripheral nerve stimulation,brain stimulation techniques have also been developed for patients with epilepsy recently.Anumber of therapies have been developed in the past decades.About two thirds of patients can be seizure free with antiepileptic drugs.1 Other patients are drug resistant,some of whom are good candidates for epileptic focus resection and become seizure free after surgery.2 The treatment for drug-resistant patients who are not eligible for resection is still challenging.Traditionally,these patients can receive palliative surgery such as callosotomy and multiple subpial transection,3,4 but the long-term outcomes of these procedures are not satisfactory.5-7 In the past decades,neuromodulation techniques have been applied in the treatment of epilepsy.Much evidence has been accumulated about the therapeutic effects of vagus nerve stimulation for epilepsy.In contrast to peripheral nerve stimulation,brain stimulation techniques have also been developed for patients with epilepsy recently.

关 键 词：sleep deprivation DEPRESSION POLYSOMNOGRAPHY executive function 

分 类 号：R749.4[医药卫生—神经病学与精神病学]