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作 者:俞媛洁[1] 陈继红[1] 于文蓁[1] 谭诗云[1] 罗和生[1]
机构地区:[1]武汉大学人民医院消化内科,湖北武汉430060
出 处:《武汉大学学报(医学版)》2014年第5期797-800,共4页Medical Journal of Wuhan University
摘 要:目的:探讨罗马Ⅲ分类中功能性消化不良餐后不适综合征(PDS)患者体表胃慢波信号特征。方法:20例无症状健康受试者,55例符合罗马Ⅲ诊断标准的功能性消化不良餐后不适综合征患者,经Medtronic胃电检测系统连续记录空腹及餐后体表胃电信号30min,获取慢波主频率(DF)、主功率(DP)、正常慢波百分比(N%)等参数,组间参数进行t检验。结果:1PDS患者胃慢波主频率较健康受试者快,主功率较健康受试者低[(3.08±0.28)次/min vs(2.95±0.24)次/min,P<0.01;(44.57±5.69)dB vs(46.92±5.61)dB,P<0.01]。2PDS患者胃节律紊乱百分比较健康受试者高,且胃正常节律百分比及胃慢波耦合百分比较健康受试者低[(8.39±6.06)%vs(15.82±11.53)%,P<0.01;(89.41±6.42)%vs(76.99±23.02)%,P<0.01;(55.19±16.22)%vs(40.95±23.39)%,P<0.01]。3PDS患者餐后胃慢波主频率较餐前快,主功率较餐前高[(3.08±0.28)次/min vs(3.13±0.80)次/min,P<0.01;(44.57±5.69)dB vs(47.29±13.70)dB,P<0.01]。4餐前、餐后PDS患者胃正常慢波百分比、节律紊乱百分比及慢波耦合百分比无显著性差异。结论:PDS患者胃慢波活动存在异常。Objective:To characterize the gastric slow wave signal recorded in postprandial distress syndrome(PDS).Methods:Lectrogastrography(EGG,Medtronic,USA)was performed to record the preprandial and postprandial percutaneous gastric slow wave signal for 30 min in 20 healthy controls and 55 patients with functional dyspepsia subtype of PDS.EGG parameters included dominant frequency and power,percentage of normal gastric slow waves,percentage of gastric dysrhythmias,and percentage of power distribution.Data were expressed as mean±SD,and all parameters were compared using the T-test.Results:1Patients with PDS showed a higher gastric dominant frequency and a lower dominant power than controls([3.08±0.28]beats/min vs[2.95±0.24]beats/min,P〈0.01;[44.57±5.69]dB vs[46.92±5.61]dB,P〈0.01).2Patients with PDS presented a lower percentage of normal gastric slow waves and power distribution,but a higher percentage of gastric dysrhythmias than controls([8.39±6.06]%vs[15.82±11.53]%,P〈0.01;[89.41±6.42]%vs[76.99±23.02]%,P〈0.01;[55.19±16.22]%vs[40.95±23.39]%,P〈0.01).3Patients with PDS in the postprandial condition showed a higher gastric dominant frequency and dominant power than preprandial condition([3.08±0.28]beats/min vs[3.13±0.80]beats/min,P〈0.01;[44.57±5.69]dB vs[47.29±13.70]dB,P〈0.01).4There was no significant difference between preprandial and postprandial in the percentage of normal gastric slow waves,gastric dysrhythmias and power distribution in the patients with PDS.Conclusion:Gastric slow wave activity of PDS showed significant difference from controls which may affect their gastric motility.
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