不同视网膜静脉阻塞患眼视盘水平径及杯盘比差异观察  

The differences of horizontal optic disc diameter and cup/disc ratio in eyes with different kinds of retinal vein occlusion

作　　者：杨丽亚 徐延山[2] 杨凯转[3] 杨旭 韩梅[2] 

机构地区：[1] 南阳市眼科医院 [2]天津市眼科医院天津市眼科学与视觉科学重点实验室天津市眼科研究所天津医科大学眼科临床学院,300020 [3] 郑州市第二人民医院眼科

出　　处：《中华眼底病杂志》2014年第5期458-461,共4页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的 观察不同视网膜静脉阻塞（RVO）患眼视盘水平径、杯盘比（C/D）差异.方法 荧光素眼底血管造影（FFA）检查确诊的RVO患者385例392只眼纳入研究.其中,男性192例,女193例;平均年龄（58.30±11.51）岁;病程7 d～1个月.依据是否合并糖尿病（DM）、高血压（HP）将患眼分为单纯RVO组、RVO合并DM组、RVO合并HP组,分别为356、20、16只眼.选取同期FFA检查正常的100只眼作为正常组.单纯RVO组356只眼中,视网膜分支静脉阻塞（BRVO） 201只眼;视网膜中央静脉阻塞（CRVO） 100只眼;半侧视网膜静脉阻塞（H-CRVO） 17只眼;黄斑分支静脉阻塞（M-BRVO） 38只眼.非缺血型RVO 101只眼.其中,BRVO 17只眼;CRVO 53只眼;H-CRVO 6只眼;M-BRVO 25只眼.缺血型RVO 255只眼.其中,BRVO 184只眼;CRVO 47只眼;H-CRVO 11只眼;M-BRVO 13只眼.采用德国海德堡共焦激光眼底造影系统行红外眼底照相（IR）,利用系统自带软件在IR 30＆#176;图像上测量患眼视杯、视盘水平径,计算水平径C/D.结果 正常组、单纯RVO组、RVO合并DM组、RVO合并HP组视盘水平径比较,差异无统计学意义（F=1.17,P＞0.05）;C/D比较,差异有统计学意义（F=82.24,P＜0.05）.正常组与单纯RVO组中BRVO、CRVO、H-CRVO、M-BRVO患眼视盘水平径（F=4.49）、C/D（F=61.40）比较,差异均有统计学意义（P＜0.05）.与正常组视盘水平径比较,CRVO眼视盘水平径相对较小,差异有统计学意义（P＜0.05）;BRVO、M-BRVO、H-CRVO眼视盘水平径相对较大,但差异无统计学意义（P＞0.05）.BRVO、CRVO、H-CRVO、M-BRVO患眼C/D与正常组比较,差异均有统计学意义（P＜0.05）.单纯RVO组中,不同分型RVO眼视盘水平径与正常组比较,差异有统计学意义（F=3.94,P＜0.05）;C/D比较,差异有统计学意义（F=33.16,P＜0.05）.RVO同一分型眼间视盘水平径两两比较,除缺血型H-CRVO眼与非缺血型H-CRVO眼视盘水平径之间差异有统计学意义（P＜0.05）外,其余�Objective To observe the differences of horizontal optic disc diameter and cup/disc （C/D） ratio in eyes with different kinds of retinal vein occlusion （RVO）.Methods A total of 392 eyes from 385 RVO patients diagnosed by fundus fluorescein angiography （FFA） were included in this study.The patients included 192 males and 193 females.The average age was （58.30±11.51） years.The disease duration was from 7 days to 1 month.The eyes were divided into RVO group （356 eyes）,RVO combining diabetes mellitus （DM） group （20 eyes） and RVO combining high blood pressure （HP） group （16 eyes）.One hundred normal eyes examined by FFA in the same testing period were selected as the control group.Among the 356 eyes in the RVO group,there were 201 eyes with branch RVO （BRVO）,100 eyes with central RVO （CRVO）,17 eyes with hemi CRVO （H-CRVO）,and 38 eyes with macular BRVO （M-BRVO）.Among the 101 non-ischemic RVO eyes,there were 17 eyes with BRVO,53 eyes with CRVO,6 eyes with H-CRVO,and 25 eyes with M-BRVO.Among the 255 ischemic RVO eyes,there were 184 eyes with BRVO,47 eyes with CRVO,11 eyes with H-CRVO and 13 eyes with M-BRVO.The diameter of optic cup and disk,and the C/D ratio was measured on fundus infrared radiation （IR） IR30＆#176;image by Heidelberg confocal laser fundus imaging system.Results There was no significant difference of horizontal optic disc diameter among 4 groups （F=1.17,P〉0.05）.The difference of C/D ratio was significant among 4 groups （F=82.24,P〈0.05）.The differences of horizontal optic disc diameter and C/D ratio in different kinds of RVO in normal group and RVO group were significant （F=4.49,61.396; P〈0.05）.The horizontal optic disc diameter of eyes with CRVO was a little smaller than normal eyes （P〈0.05）.There was no difference of horizontal optic disc diameter between the eyes with BRVO,M-BRVO,H-CRVO and normal eyes （P〉0.05）.The difference of C/D ratio was significant between the eyes with BRVO,CRVO,M-BRVO,H-CRVO and normal eyes

关 键 词：视网膜静脉闭塞/病因学 视盘 

分 类 号：R774.1[医药卫生—眼科]