老年黄斑变性的治疗新进展  

Recent advance in therapies for age-related macular degeneration

作　　者：周洁[1] 吴伟珍[1] 曹晓禄 王宏彬[1] 

机构地区：[1]首都医科大学附属北京友谊医院眼科,中国北京市100050

出　　处：《国际眼科杂志》2014年第10期1812-1814,共3页International Eye Science

摘　　要：老年黄斑变性(age-related macular degeneration,AMD)是西方国家白种人不可逆性视力下降的首要原因。目前,AMD的治疗方法主要有抗血管内皮生长因子抗体(Anti-vascular endothelial growth factor,Anti-VEGF)的药物治疗、光动力学疗法(photodynamic therapy,PDT)、局部应用曲安奈德(triamcinolone acetonide,TA)及激光治疗(纳秒激光等)等。本文通过对比分析老年黄斑变性的不同治疗方法的作用原理、治疗效果、副作用、经济成本,为临床治疗提供依据。Age - related macular degeneration （ AMD ） is the leading cause of irreversible visual loss in elderly people among white - dominated population. At percent, treatment for AMD includes anti - vascular endothelial growth factor antibody （ Anti- VEGF ） drug treatment, photodynamic therapy （ PDT ） , topical application of triamcinolone acetonide （ TA ） and laser therapy （ nanosecond laser） etc. Through comparative analysis of different treatment methods of AMD, we review the mechanism, clinical efficacy, adverse events and cost effectiveness to provide the basis for clinical treatment.

关 键 词：老年黄斑变性 光动力学疗法 曲安奈德 

分 类 号：R774.5[医药卫生—眼科]