放疗联合热疗治疗骨转移癌的疗效及不良反应观察  

The observation of the efficacy and adverse reactions of bone metastases treating by radiotherapy combined thermal therapy

作　　者：徐凤春[1] 王媛媛[1] 

机构地区：[1]北京市房山区第一医院,北京102400

出　　处：《基层医学论坛》2014年第28期3777-3778,共2页The Medical Forum

摘　　要：目的探讨放疗联合热疗治疗骨转移癌的疗效及不良反应。方法将70例骨转移癌患者随机分为放疗联合热疗组(R+H)和单纯放疗组(R),2组分别给予骨转移疼痛部位放疗联合热疗和单纯放疗,2组放疗时射线能量均为6 MV-X,总剂量均为30 Gy/10次。R+H组在患者放疗结束后30 min内进行热疗,每周2次,每次45 min,共4次。治疗结束后观察2组不良反应发生率,并采用数字评分法(NRS)评估患者疼痛程度。结果疼痛缓解率R+H组高于R组(P<0.05),白细胞减少发生率低(P<0.05),且未增加其他不良反应发生率(P>0.05)。结论放疗联合热疗可提高骨转移癌的疗效且不增加不良反应。Objective To study the efficacy and adverse reactions of bone metastases treated by radiotherapy combined thermal therapy. Methods 70 cases of bone metastases were randomly divided into radiotherapy combined thermal therapy group （R＋H） and simple radiotherapy group （R）.Results The pain relief rate of H＋R group was higher than R group （P〈0.05）, the incidence of white blood cells reduced was lower （P〈0.05）, and other adverse reaction rate did not increase （P〉0.05）.Two groups of radiotherapy adopted 6 MV-X-ray, and total dose was 30 Gy/10f. Thermal therapy begin within 30 minutes after radiation therapy,2 times a week,45 minutes at a time,a total of four times.We observed two groups incidence of adverse reactions at the end of the treatment,and used the NRS（digital scoring method） evaluate the pain degree of patients. Conclusion Radiotherapy combined thermal therapy could improve the curative effect and the quality of life of patients with bone metastases, and not increase the incidence of adverse reactions.

关 键 词：骨转移癌 放疗 热疗 疗效 副反应 

分 类 号：R738.1[医药卫生—肿瘤]