氯吡格雷与小剂量尿激酶联合治疗急性进展性脑梗死的临床观察  

The Clinical Observation of Clopidogrel Combined with Low dose of Urokinase on Acute Progressive Cerebral Infarction

作　　者：李海鹰 

机构地区：[1]广东省揭阳市揭西县人民医院急诊科,广东揭阳515400

出　　处：《中国医药指南》2014年第28期54-55,共2页Guide of China Medicine

摘　　要：目的探讨氯吡格雷与小剂量尿激酶联合治疗急性进展性脑梗死临床效果。方法 98例进展性脑梗死患者随机分为观察组和对照组。对照组给予常规治疗,观察组给予氯吡格雷与小剂量尿激酶联合治疗。观察两组治疗效果。结果观察组治疗14 d后的神经功能缺损评分和同期的对照组神经功能缺损评分比较,差异有统计学意义(P<0.05)。观察显效率和有效率分别高于对照组的显效率和有效率,差异有统计学意义(P<0.05)。结论氯吡格雷与小剂量尿激酶联合治疗急性进展性脑梗死临床效果显著,值得借鉴。ObjectiveTo explore the clinical effect of clopidogrel combined with low dose of urokinase on acute progressive cerebral infarction.Methods 98 patients with progressive cerebral infarction wereselected and randomly divided into observation group and control group. The control group was given conventional treatment, the observation group was given clopidogrel with low dose of urokinase. the therapeutic effect of two groups was observed. Results The score of nervous function defect in the observation group after 14 days treatment compared with that in control group after 14 days treatment at the same period, the difference was statistically significant （P〈0.05）.The significant efficiency and efficiency in the observation group were higher than those in the control group, the difference was statistically significant （P〈0.05）.Conclusion The clinical effect of clopidogrel with low dose of urokinase in the treatment of acute progressive cerebral infarction is significant, and which is worthy of reference.

关 键 词：进展性脑梗死 氯吡格雷 尿激酶 

分 类 号：R743.33[医药卫生—神经病学与精神病学]