老年2型糖尿病合并脑梗死患者血清代谢指标分析  

Analysis on metabolism indicators in elderly patients combined with type 2 diabetes mellitus and cerebral infarction

作　　者：田慧军[1] 康玲伶[2] 余剑[3] 

机构地区：[1]中国人民解放军第309医院神经内科,北京100091 [2]承德医学院附属医院神经内科,河北承德067000 [3]中山大学附属第一医院神经内科,广州510080

出　　处：《检验医学与临床》2014年第18期2545-2547,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨老年2型糖尿病(T2DM)合并脑梗死患者血清胆红素、尿酸(UA)和血脂水平的变化及临床意义。方法随机选择82例老年患者,按疾病种类分为T2DM合并脑梗死组、单纯脑梗死组和单纯T2DM组,检测并比较血清胆红素、UA、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平。结果与单纯脑梗死组和单纯T2DM组比较,T2DM合并脑梗死组总胆红素、间接胆红素、HDL-C水平明显降低,UA、TC、TG、LDL-C水平明显升高(P<0.05)。结论血清胆红素水平降低、高尿酸血症及血脂代谢异常可能与T2DM患者继发脑梗死密切相关。Objective To investigate changes and clinical significance of serum levels of bilirubin,uric acid（UA）and lipids in elderly patients combined with type 2diabetes mellitus（T2MD）and cerebral infarction.Methods Serum levels of bilirubin,UA,total cholesterol（TC）,triglyceride（TG）,high-density lipoprotein cholesterol（HDL-C）and low-density lipoprotein cholesterol（LDL-C）were measured and compared among 82 randomly selected elderly patients,whom were divided into three groups,including T2 DM combined with cerebral infarction group,simple cerebral infarction group and simple T2 DM group.Results Compared with simple cerebral infarction group and simple T2 DM group,serum levels of total bilirubin,indirect bilirubin and HDL-C in T2 DM combined with cerebral infarction group were significantly lower,but serum levels of UA,TC,TG and LDL-C were significantly higher（P〈0.05）.Conclusion Lower serum level of bilirubin,hyperuricemia and abnormality of lipids metabolism might be closed related with incidence of cerebral infarction in patients with T2 DM.

关 键 词：2型糖尿病 胆红素 尿酸 血脂 

分 类 号：R575[医药卫生—消化系统]