Cajal间质细胞与胃肠动力关系的研究进展  

Relationship between interstitial cells of Cajal and gastrointestinal motility

作　　者：李泽培[1] 邱野[1] 彭燕[1] 

机构地区：[1]泸州医学院附属医院消化内科,四川泸州646000

出　　处：《胃肠病学和肝病学杂志》2014年第9期983-986,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：Cajal间质细胞(interstitial cells of Cajal,ICC)是胃肠慢波的起搏细胞,具有产生慢波、传导慢波电位、调节神经递质等功能,是调节胃肠动力的重要环节。ICC在维持正常胃肠动力方面发挥着重要作用,同时其形态、数量及分布的改变会导致多种胃肠动力障碍性疾病。一些以ICC为靶向治疗胃肠动力性疾病药物的研究也取得一定进展。本文就近年来ICC与胃肠动力关系的研究进展作一概述。Interstitial cells of Cajal （ICC） are the pacemakers of gastrointestinal tract,which can generate electricity signal,conduct slow wave and regulate the neurotransmitters.ICC play important roles in maintaining the normal gastrointestinal motility,while changes of morphology,number and distribution will lead to a variety of gastrointestinal kinetic disorder.Some study regard ICC as treatment target for gastrointestinal kinetic disorder have made some progress.In this paper,we will review recent progress in the relationship between ICC and gastrointestinal motility.

关 键 词：CAJAL间质细胞 肠神经系统 胃肠动力 

分 类 号：R573.9[医药卫生—消化系统]