非糜烂性胃食管反流病与幽门螺杆菌感染的相关性研究  

The relationship between non-erosive gastroesophageal reflux disease and Helicobacter pylori infection

作　　者：吴晓锐 涂铭 陈亮 郑林 王炘 詹志刚 

机构地区：[1]南京军区九二医院消化内科,福建南平353000

出　　处：《胃肠病学和肝病学杂志》2014年第9期1008-1009,共2页Chinese Journal of Gastroenterology and Hepatology

基　　金：南京军区医药卫生科研基金课题(07M061)

摘　　要：目的探讨非糜烂性胃食管反流病(non-erosive gastroesophageal reflux disease,NERD)与幽门螺杆菌(Helicobacter pylori,H.pylori)感染的关系。方法将确诊为军人NERD患者156例(A组)、军人慢性浅表性胃炎患者120例(B组)和军人十二指肠球部溃疡患者60例(C组),予活检胃窦组织快速尿素酶法及14C呼气试验法进行H.pylori检测;比较A组与B组、C组H.pylori感染情况。结果 A组H.pylori感染率12.82%,B组H.pylori感染率68.33%,C组H.pylori感染率85.00%,A组感染率明显低于B组、C组,差异均有显著统计学意义(P<0.01)。结论 NERD发生时,H.pylori感染几率明显减小。Objective To investigate the relationship between non-erosive gastroesophageal reflux disease （NERD） and Helicobacter pylori （H.pylori） infection.Methods One hundred and fifty-six soldier patients with NERD （group A）,120 soldier patients with chronic superficial gastritis （group B） and 60 soldier patients with duodenal bulbar ulcer （group C） were checked by rapid urase test with gastric antrum biopsy and ^14C-UBT.The H.pylori infection in group A,group B,group C were compared.Results The infection rate of H.pylori in group A （12.82%） was lower than that in group B （68.33%） and group C （85.00%）,there were significant differences （P 〈 0.01）.Conclusion When NERD occurs,the probability of H.pylori infection will be reduced.

关 键 词：胃食管反流病 幽门螺杆菌 感染 军事人员 

分 类 号：R57[医药卫生—消化系统]