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出 处:《临床放射学杂志》2014年第9期1368-1371,共4页Journal of Clinical Radiology
摘 要:目的探讨恶性肿瘤患者肾上腺大小与正常人群间是否存在差异。方法搜集在本院行上腹部CT检查的患者101例,测量肾上腺的最大径。其中肿瘤患者62例(男42例,女20例,年龄46~83岁),搜集两次检查图像,第一次为手术前或术后第1次复查(一般小于3个月),第二次为间隔一年半(18个月)以上复查,根据有无复发转移分为治愈组(P,Past),治愈组(N,Now),未愈组(P),未愈组(N);非肿瘤检查者39例(男15例,女24例,年龄22~86岁),归为对照组。将不同组别进行分析比较。结果肿瘤患者过去和现在之间比较,治愈组(P-N)肾上腺大小不存在差异(P〉0.05),未愈组(P-N)则存在差异(P〈0.05)。未愈组(P),治愈组(P、N)与对照组间不存在差异(P〉0.05)。各组男女间不存在差异(P〉0.05)。结论恶性肿瘤患者往往都会伴随着焦虑、抑郁等不良情绪,这些情绪通过下丘脑-垂体-肾上腺轴影响肾上腺的功能,促进相关激素的分泌,长期的不良情绪最终会造成肾上腺体积的增大。在日常工作中要认识这种变化,避免误诊。Objective To clarify whether any difference in adrenal size exists between patients with malignancies and the normal population. Methods A total of 10l patients who had received upper abdominal CT scanning at authors' de- partment were enrolled in this study. The maximum diameters of adrenal glands were measured. Among the 101 patients, 62 suffered from malignancies, including 42 males and 20 females, aged from 46 - 83 years. The images of two times of ex- aminations were collected. The initial check was the preoperative one or the first follow-up check after surgery (usually within three months). The second examination was performed 18 months after the surgery. According to the presence or ab- sence of recurrence and metastasis, the patients were divided into the past cured group ( P, Past) , present cured group (N, Now), past uncured group (P) and present uncured group (N). Other 39 patients having no malignancies were used as the control group (15 males and 24 females, aged 22 -86 years). The results were analyzed and compared between each other among the all groups. Results No statistically significant differences in the size of adrenal glands existed be- tween past cured group and present cured group ( P 〉 0.05 ) , while statistically significant differences in the size of adrenal glands existed between past uncured group and present uncured group ( P 〈 0.05 ). Also no statistically significant differ- ences in the size of adrenal glands existed between the control group and each of the other four groups ( P 〉 0.05 ). No sta- tistically significant differences in the size of adrenal glands existed between males and females in each group ( P 〉 0.05 ). Conclusion Patients with malignancies are often accompanied by anxiety, depression and other unhealthy emotions. These bad emotions will affect adrenal functions through the hypothalamus-hypophysis-adrenal axis, thus to promote the se- cretion of related hormones. Unhealthy emotions over a long period of time wil
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