全身皮疹-骨痛-多发椎体压缩性骨折  

Rash-bone pain-multiple vertebral compression fractures

作　　者：吕芳[1] 刘怡[1] 周沛然[1] 马豆豆 夏维波[1] 邢小平[1] 姜艳[1] 王鸥[1] 李梅[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院内分泌科卫生部内分泌重点实验室,北京100730

出　　处：《中华骨质疏松和骨矿盐疾病杂志》2014年第3期271-276,共6页Chinese Journal Of Osteoporosis And Bone Mineral Research

基　　金：国家自然科学基金(81100623);国家临床重点专科课题(WBYZ 2011-873)

摘　　要：骨质疏松是糖皮质激素常见而严重的不良反应,可引起骨骼疼痛、增加骨折风险、降低患者生活质量。本文分析1例因全身皮疹误诊为自身免疫内分泌多腺体综合征,长期服用糖皮质激素导致严重骨质疏松症病例,旨在加深对糖皮质激素诱导骨质疏松症的认识,明晰自身免疫内分泌多腺体综合征的诊断。Osteoporosis is the common and severe side effect of glucocorticoid hormone , which causes bone pain and increases the risk of fracture and impairs the life quality of patients.We analyzed a patient with severe osteopo-rosis induced by long term treatment of glucocorticoid hormone , after he was misdiagnosed as autoimmune polyendocrine syndrome （ APS） .We aim to improve the understanding of glucocorticoid-induced osteoporosis and to clarify the diag-nosis of APS.

关 键 词：糖皮质激素 骨质疏松症 自身免疫内分泌多腺体综合征 

分 类 号：R681[医药卫生—骨科学]