老年睡眠期周期性腿动患者的血脂水平分析  

Serum lipid levels in aged patients with periodic limb movements during sleep

作　　者：侯晓平[1] 王玉军[1] 张婧[1] 缪京莉[1] 马艳敏[1] 

机构地区：[1]空军总医院干部病房,北京100142

出　　处：《中国临床保健杂志》2014年第5期451-453,共3页Chinese Journal of Clinical Healthcare

摘　　要：目的研究老年睡眠期周期性腿动(PLMS)患者的血脂水平改变。方法采用微动敏感床垫睡眠监测系统检测60岁以上老年住院心血管病患者睡眠呼吸暂停低通气综合征(SAHS)和PLMS,调查患者心血管疾病及等危症、服用他汀类药物情况,检测血脂成分并分析。结果 104例SAHS患者进入本研究,平均年龄(76.6±6.7)岁,PLMS患者46例。在患者年龄、性别、患心血管疾病和(或)糖代谢异常、服用他汀类药物病例数和睡眠呼吸紊乱参数、夜间血氧水平相近的情况下,PLMS组血清总胆固醇水平显著低于非PLMS组[(4.46±0.88)mmol/L比(4.84±0.94)mmol/L,P<0.05]。结论老年PLMS患者血清总胆固醇水平较非PLMS患者低,这种血清总胆固醇的降低可能具有一定的临床意义。Objective To investigate the serum lipid levels in aged patients with periodic limb movements during sleep（ PLMS）. Methods Sleep breathing and limb movements were monitored by micro-movement sensitive mattress sleep monitoring system among patients aged 60 years or more with cardiovascular disease（ CVD） and CVD risk equivalents. The clinical data and serum lipid levels were analyzed. Results One hundred and four patients with sleep apnea-hypopnea syndrome（ SAHS） were recruited in this study. The average age of patients was（ 76. 6 ± 6. 7）years. Forty-six cases were PLMS. The level of serum total cholesterol（ TC） in patients with PLMS was significantly lower than in patients thoses without PLMS,（ 4. 46 ± 0. 88） mmol /L vs（ 4. 84 ± 0. 94） mmol /L,P 〈0. 05. There were no significant differences in patients＇ age,sex,prevalence of CVD and CVD risk equivalents,and parameter of sleep-disordered breathing between the two groups. Conclusion The level of serum TC decreased in patients with PLMS. Its mechanism and clinical significance remains to be defined.

关 键 词：睡眠呼吸暂停 阻塞性 夜间性肌阵挛综合征 胆固醇 老年人 

分 类 号：R740[医药卫生—神经病学与精神病学]