某医院全年病原菌分布及耐药性分析  

Distribution and drug resistance of the pathogens in a hospital all year round

作　　者：黄苏姗[1] 贾进明[1] 陈听娣[1] 

机构地区：[1]江苏省常州市第三人民医院急诊科,江苏常州213000

出　　处：《现代预防医学》2014年第19期3566-3568,3625,共4页Modern Preventive Medicine

摘　　要：目的通过分析2012年常州市第三人民医院住院部患者感染的病原菌分布及耐药情况,为临床使用抗生素提供指导意义。方法回顾性分析从本院住院部2012年收治的348名患者中所分离出的病原菌及药敏试验结果。结果共分离出病原菌431株。痰液分离率最高(30.4%)。革兰阴性菌239株(55.5%),革兰阳性菌188株(43.6%),0.9%为真菌。革兰阴性菌主要为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、鲍曼不动杆菌和阴沟肠杆菌。革兰阳性菌主要为表皮葡萄球菌、金黄色葡萄球菌、溶血葡萄球菌和人葡萄球菌。革兰阴性菌对阿米卡星、亚胺培南、美洛培南及厄他培南等较敏感,大肠埃希菌、肺炎克雷伯菌产超广谱β-内酰胺酶(ESBLs)的分别为57.14%和31.03%,未发现耐利奈唑烷的革兰阳性球菌。结论加强耐药菌的监测,对临床用药有重大意义。Objective To analyze the distribution and the drug resistance of infective bacteria from our hospital in 2012,to give a guide for the clinical use of antibiotics.Methods All pathogens isolated from over 348 inpatients and the results of drug susceptibility were analyzed.Results 431 pathogenic bacteria were isolated,including 239 gram-negative bacteria（55.5%） and 188gram-positive ones（43.6%）,0.9% were fungus.The most of gram-negative bacteria were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,Acinetobacter baumannii and Enterobacter cloacae.The most of gram-positive ones were Staphylococcus epidermidis,Staphylococcus aureus,Staphylococcus haemolyticus and Staphylococcus hominis.The gram-negative bacteria were sensitive to amikacin,imipenem,meropenem and ertapenem.57.14% of Escherichia coli produced ESBLs and so did 31.03% of Klebsiella pneumoniae.Conclusion Strengthening the inspection of the pathogens helps a lot to the clinical use of antibiotics.

关 键 词：病原菌 分布 耐药率 抗生素 

分 类 号：R117[医药卫生—公共卫生与预防医学]