MSCT测量肝硬化体积与肝脏储备功能关系研究  

Research on the relationship between multi-slice spiral CT measurement of cirrhosis volume and liver functional reserve

作　　者：张艳[1,3] 袁军 孙兴旺[3] 邹泽[1] 

机构地区：[1]陕西省人民医院1CT室 [2]俭验科,陕西西安710068 [3]西安交通大学第一附属医院影像中心

出　　处：《实用放射学杂志》2014年第9期1498-1501,共4页Journal of Practical Radiology

摘　　要：目的 探讨肝硬化患者肝脏体积（LV）的变化趋势及与肝功能有关指标的相关性.方法 收集在本院接受MSCT扫描肝硬化患者45例,测量、分析LV数值范围的差异;收集MSCT检查前1周内的肝功能指标谷丙转氨酶（ALT）、谷草转氨酶（AST）、总胆红素（TBIL）、白蛋白（ALB）和凝血酶原时间（PT）的检验结果.设定P值,检验是否具有统计学意义.结果 肝硬化A、B、C级LV数值分别为（985.87±147.29）cm3、（818.77±138.49）cm3、（677.01±118.58）cm3,各级之间体积差异具有统计学意义（P＜0.05）.A级中LV与肝功能指标均没有密切的相关关系（P＞0.05）,B级中LV与ALB呈正相关（r=0.548,P＜0.05）,与ALT、AST、TBIL（P＞0.05）及PT（r=-0.508,P＜0.05）呈负相关,与ALB、PT的相关系数r具有统计学意义;C级中与各项指标均有密切的相关关系,与ALB呈正相关（r=0.545,P＜0.05）,与ALT（r=-0.711,P＜0.05）、AST（r=-0.537,P＜0.05）、TBIL（r=-0.878,P＜0.05）及PT（r=-0.597,P＜0.05）呈负相关.结论 肝硬化时LV数值与临床常规肝功能检查指标之间有一定的相关性,MSCT测量方法能定量评价LV变化,评价病肝储备功能状况具有一定的参考价值.Objective To study the correlation between liver volume （LV） of cirrhosis and clinical index of hepatic function. Methods 45 hospitalized patients with liver cirrhosis were collected. The LV were measured and the ranges of all data were ob- served. Then the clinical index of liver function alanine transaminase （ALT） 、glutamie-oxalacetic transaminase （AST） ,total bilirubin （TBIL） ,albumin （ALB） and prothrombin time（PT） were collected. Statistics analysis were performed between LV and index of liv- er function. Results The average of LV in cirrhosis were（985.87±147.29）cm3）Child A group）,（818.77±138.49）cm3（Child B group） and（677.01±118.58）cm3 （Child C group） , there were of statistically difference（P〈0.05） between different group. The LV of classes A was not significantly correlated with clinical index of liver function（P〉0.05）. The I.V of classes B was positively corre- lated to the ALB（r=0.548,P〈0.05） , correlated with ALT,AST ,TBIL（P〉0.05）,PT（r=-0.508,P〈0.0S）.The I.V of pa- tients in Child C group was significantly correlated with ALB（ r= 0. 545, P〈 0.05 ）, ALT（ r= - 0.711, P〈0.05 ）, AST （ r= - 0.537, P%0.05 ）, TBIL （ r= - 0. 878, P〈0.05 ）, PT （ r=- 0. 597, P〈0.05 ）. Conclusion It is correlation with LV of cirrhosis and clini- cal index of liver function. The volume changes of liver can be obtained by MSCT scan, whicb is helpful for better understanding pa tient ,sliver functional reserve.

关 键 词：肝脏体积测量 肝硬化 肝功能试验 计算机体层成像 

分 类 号：R575.2[医药卫生—消化系统] R814.42[医药卫生—内科学]