MSCT和^(18)F-FDGPET-CT显像对食管癌术前分期诊断的价值  

Diagnostic and application value of MSCT and ^(18)F-FDG PET-CT scans in preoperative staging of esophageal cancer

作　　者：李爽[1] 吕维富[1] 汪世存[1] 潘博[1] 倪明[1] 

机构地区：[1]安徽医科大学附属省立医院影像科,合肥230001

出　　处：《安徽医科大学学报》2014年第10期1495-1498,共4页Acta Universitatis Medicinalis Anhui

基　　金：安徽省卫生厅医学科研课题计划(编号:13ZC020)

摘　　要：经内镜和病理证实并接受手术治疗的182例食管癌患者入组,患者均在术前1周接受多层螺旋CT(MSCT)和氟代脱氧葡萄糖正电子发射断层扫描CT(18F-FDG PET-CT)扫描,结合图像信息,记录其术前分期,并与术后病理结果比较。MSCT与18F-FDG PET-CT扫描对判断T分期准确率的差异无统计学意义(χ2=0.540,P=0.463),而18F-FDG PETCT扫描对判断N分期的灵敏度、特异度及准确率均高于MSCT(P<0.05);术前MSCT扫描检测T、N分期与术后病理一致性差(Kappa=0.376,Kappa=0.317,P<0.01),而术前18F-FDG PET-CT扫描检测N分期与术后病理高度一致(Kappa=0.750,P<0.01)。The clinical data obtained from 182 cases with esophageal cancer proved by pathology endoscopy were retrospectively analyzed, which were treated with surgery. Multi-slice computer tomography（ MSCT） and 18 F-FDG positron emission tomograp-hy combined computed tomography（18 F-FDG PET-CT） scans were underwent for the patients within one week before treatment;combined with the images to record the preoperative MSCT and 18 F-FDG PET-CT staging,TNM staging of the patients with operation was compared with post-operative pathological results based on various imaging findings. In comparison to post-operative pathological results,the difference between accu-racy of T staging diagnosed by MSCT and PET-CT was no significance （P〈0.05）,but the sensitivity,specificity and accuracy of regional lymph node metastases diagnosed by PET-CT had an advantage over that by MSCT （ P〈0.05）. The Kappa values for MSCT scans in T and N staging diagnosis were not ideal（Kappa〈0.40,P〈0.01）, but it was favorable for preoperative PET-CT scans in N staging diagnosis（Kappa〉0. 40,P〈0.01）.

关 键 词：食管肿瘤 体层摄影术 肿瘤分期 诊断 评价研究 

分 类 号：R730.44[医药卫生—肿瘤] R817.4[医药卫生—临床医学]