计算机辅助色素内镜诊断早期食管癌的价值  

Computer aided chromoendoscopy for diagnosis of early esophageal cancer

作　　者：叶武[1] 刘鹏飞[1] 曹向明[2] 沈卫东[1] 陆小锋[3] 钱建忠[4] 徐娟[1] 

机构地区：[1]东南大学医学院附属江阴医院消化内科,江苏省江阴市214400 [2]东南大学医学院附属江阴医院肿瘤科,江苏省江阴市214400 [3]上海大学通信与信息工程学院,上海市200072 [4]东南大学医学院附属江阴医院病理科,江苏省江阴市214400

出　　处：《世界华人消化杂志》2014年第25期3811-3814,共4页World Chinese Journal of Digestology

摘　　要：目的:探讨计算机辅助色素内镜诊断早期食管癌的价值.方法:应用Lugols碘液对115例患者食管的可疑病灶进行染色后采集图像及取病理,应用计算机的颜色定量分析软件对黏膜颜色变化进行定量分析,并与病理结果进行比较.结果:115例患者共发现135个异常染色灶,其中炎性病变83个,癌性病变52个.3种颜色空间中主要参数G、U、V诊断食管癌的敏感性分别为82.7%(43/52)、88.5%(46/52)、80.8%(42/52),特异性分别为83.1%(69/83)、86.7(72/83)、84.3(70/83).结论:计算机辅助色素内镜能较好地反映病灶的病理性质,能避免术者的主观性,提高活检检查的准确性和食管早癌的诊断率.AIM： To assess the diagnostic value of computer aided chromoendoscopy for early esophageal cancer.METHODS： One hundred and fifteen patients with suspected esophageal diseases were involved in this study. The lesions were first sub-jected to Lugols staining, and then biopsies were performed in the lesions. Quantitative analysis of the color change of lesions was performed using software. RESULTS： A total of 135 iodine-unstained lesions were found in 115 patients. Among these, 83 lesions were diagnosed as inflammatory diseases, 52 lesions were diagnosed as carcinoma diseases. The sensitivities of the main color parameters G, U and V in the three color space were 82.7%（43/52）, 88.5%（46/52） and 80.8%（42/52）, respectively, and the specificities were 83.1%（69/83）, 86.7（72/83） and 84.3（70/83）. CONCLUSION： Computer aided chromoendoscopy is helpful in determining pathological characteristics of the lesions and can improve the accuracy of endoscopic biopsy and the diagnosis rate of early esophageal cancer.

关 键 词：计算机 色素内镜 早期食管癌 诊断 

分 类 号：R735.1[医药卫生—肿瘤]