重庆地区食管腺癌和贲门腺癌的胃镜检出率变化30年回顾分析  

Trends in incidence of esophageal and gastric cardia adenocarcinomas in Chongqing city over the past 30 years

作　　者：邵顺子 赵晶京[1] 于晓娜[1] 张昊翔[1] 沈才飞[1] 王璞[1] 夏一菊[1] 李靖文[1] 张安然[1] 徐胤[1] 彭贵勇[1] 房殿春[1] 

机构地区：[1]第三军医大学西南医院消化科,重庆400038

出　　处：《重庆医学》2014年第29期3870-3872,共3页Chongqing medicine

基　　金：国家自然科学基金项目(81170356)

摘　　要：目的回顾性分析该院30年间食管腺癌及贲门腺癌的内镜检出情况,探讨食管腺癌及贲门腺癌发病趋势。方法收集该院1983年1月至2012年12月食管腺癌和贲门腺癌患者的胃镜诊疗及病理诊断记录,统计患者的病理诊断结果、性别等相关数据,分析30年间食管腺癌和贲门腺癌患者检出率的变化。结果 30年来该院行胃镜检查435 829例,检出食管鳞癌10 301例(2.4%),食管腺癌352例(0.08%),贲门腺癌3 058例(0.70%),非贲门胃癌5 543例(1.3%)。食管腺癌检出率无论在男性还是在女性均无明显上升趋势,但食管癌构成比例[食管腺癌/(食管鳞癌+食管腺癌)]从1.90%上升至3.20%,提示食管腺癌检出率有上升趋势。贲门腺癌检出率从0.70%上升并稳定在0.81%,其中男性的检出率从0.90%上升至1.30%。贲门腺癌构成比例[贲门腺癌/(贲门腺癌+非本门腺胃癌)]从25.30%上升至38.30%。结论 30年来食管腺癌的内镜检出率无明显变化,但其构成比例呈上升趋势。贲门腺癌的内镜检出率及构成比例均呈缓慢的上升趋势,尤以男性更为明显。Objective To describe the time trend of esophageal and gastric cardia adenocarcinomas in Chongqing of China in the past 30 years .Methods The medical records of all patients who underwent gastroscopy from Janaury 1983 to December 2012 at the Southwest hospital were reviewed .The rate of endoscopic detection and proportion of adenocarcinoma in all upper gastrointestinal tumors （esophageal adenocarcinoma ,esophageal squamous cell carcinoma ,gastric cardia adenocarcinoma and gastric non-cardiac ad-enocarcinoma） were compiled and serial comparisons were made .Results 435 829 patients who underwent gastroscopy were re-viewed .Totally ,there were 352 patients with esophageal adenocarcinomas（0 .08% ） ,10 301 with esophageal squamous cell carcino-mas（2 .40% ） ,3 058 with gastric cardia adenocarcinomas（0 .70% ） and 5 543 with gastric non-cardiac adenocarcinomas（1 .30% ） .O-ver the 30-year period ,the rate of endoscopic detection of esophageal adenocarcinomas did not show a statistically significant .How-ever ,the proportion of esophageal adenocarcinomas increased from 1 .90% to 3 .20% ,suggesting an increased proportions .The rate of endoscopic detection of gastric cardia adenocarcinomas increased from 0 .70% to 0 .81% and the proportions of gastric cardia ade-nocarcinomas increased from 25 .30% to 38 .30% .Conclusion Over the 30-year period ,it seems that the incidence of esophageal adenocarcinoma had increased .An increasing trend of gastric cardia adenocarcinoma is also observed in this study ,especially in male patients .

关 键 词：食管腺癌 贲门腺癌 内窥镜检查 消化系统 构成比 

分 类 号：R735.2[医药卫生—肿瘤]