复合型黑蒜通便功能饮料对BALB/c小鼠通便功能的影响  

Laxative effects of mixed black garlic beverage on BALB / c mice

作　　者：李鑫[1] 刘锐[1] 张民[1] 

机构地区：[1]天津科技大学食品工程与生物技术学院,天津300457

出　　处：《中国食品添加剂》2014年第6期49-53,共5页China Food Additives

基　　金：十二五国家科技支撑计划重点项目课题(2012BAD33B08)

摘　　要：为研究复合型黑蒜通便功能饮料的通便效果,采用经口灌胃复合型黑蒜通便功能饮料的方法对两批BALB/c小鼠进行处理,分别测定小肠墨汁推进率和小鼠排便时间、数量、质量及肠道内大肠杆菌、肠球菌和乳杆菌的含量变化。结果显示,高、中、低剂量组小肠墨汁推进率与空白对照组和阳性对照组相比均无显著性差异(P>0.05),但与阴性对照组相比显著提高(P<0.01),其中,中剂量组效果最为明显,小肠墨汁推进率可达71.07%±9.16%。此外,与阴性对照组相比,各剂量组小鼠排便时间缩短、数量增多、质量增加;且灌胃前后各剂量组小鼠肠道内大肠杆菌和肠球菌数量差别不大,而乳杆菌数量在灌胃前后具有极显著性差异(P<0.01),表明该复合型黑蒜通便功能饮料具有良好的润肠通便功效,能够改善小鼠肠道菌群。The laxative effects of the mixed black garlic beverage on BALB/c mice was investigated by perfusing stomach with high,medium and low-dose black garlic beverage.Two groups of mice perfusing stomach 10 days and 13 days were used to determine the ink propelling rate,defecation time,quantity,weight,the amount of Escherichia coli （E.coli）,Enterococci,and Lactobacilli before and after perfusing.The results showed that the ink propelling rates of high,medium and low-dose group had no significant difference with the control group （P ＞ 0.05）,while compared with the negative group,the ink propelling rates of all dosage groups were significantly increased （P ＜0.01）.The medium-dose group showed a relative high ink-propelling rate of 71.07％ ± 9.16％.Furthermore,in comparison with the negative group,the defecation time of all dosage groups decreased,and quantity and weight increased correspondingly ; the amount of E.coli and Enterococci had a slightly increase.However,the amount of Lactobacillus had a significant difference （P ＜ 0.01） before and after perfusing stomach.These results suggested that the mixed black garlic beverage had an obvious laxative effect,which improved the intestinal flora of mice.

关 键 词：黑蒜饮料 BALB/C小鼠 排便 小肠墨汁推进率 肠道菌群 

分 类 号：TS275.4[轻工技术与工程—农产品加工及贮藏工程]