新辅助化疗与辅助化疗对乳癌病人生活质量影响比较  

NEOADJUVANT CHEMOTHERAPY VERSUS ADJUVANT CHEMOTHERAPY ON QUALITY OF LIFE IN BREAST CANCER PATIENTS

作　　者：赵真[1] 曲慧利[2] 王新刚[2] 柳晓义[2] 刘晨[2] 

机构地区：[1]首都医科大学附属北京友谊医院医疗保健中心,北京100005 [2]青岛大学附属医院乳腺病诊疗中心

出　　处：《齐鲁医学杂志》2014年第6期507-509,共3页Medical Journal of Qilu

摘　　要：目的比较新辅助化疗与辅助化疗对乳癌病人生活质量的影响。方法采用一般健康相关生活质量量表（SF-36）,分别于治疗前后对118例接受新辅助化疗和改良根治术的乳癌病人及120例接受改良根治术和辅助化疗的乳癌病人进行问卷调查。结果两组病人治疗后SF-36量表各维度评分皆明显低于治疗前（t=2.187~7.146,P〈0.01）;治疗后新辅助化疗组病人生理健康方面的生理功能、生理职能、躯体疼痛、一般健康状况4个维度和心理健康方面的精力维度评分明显高于辅助化疗组（t=2.419~3.881,P〈0.01）。结论接受新辅助化疗的乳癌病人较接受辅助化疗者可获得更好的生活质量。Objective To compare the effect of neoadjuvant chemotherapy and adjuvant chemotherapy on the quality of life in breast cancer patients. Methods Employing SF 36 survey questionnaire, a survey was carried out in 118 patients who received neo-adjuvant chemotherapy and 120 patients who received adjuvant chemotherapy before and after therapy. Results The scores of SF-36 after therapy were lower than that before （t =2.187-7.146,P〈0.01）. After therapy, the scores of PF, RP, BP, GH and VT in the patients receiving neo adjuvant chemotherapy were higher than those receiving adjuvant chemotherapy （t=2.419-3.881,P〈0.05）. Conclusion The breast cancer patients who receive neo-adjuvant chemotherapy can get a better quality of life than those receive adjuvant chemotherapy.

关 键 词：放射疗法 辅助 乳房肿瘤 生活质量 数据收集 

分 类 号：R737.9[医药卫生—肿瘤]