下咽和食管异时性重复癌  

Metachronous hypopharyngeal and esophageal multiple primary carcinomas

作　　者：胡雯[1] 许晶虹[2] 潘文胜[1,3] 

机构地区：[1]浙江大学医学院附属第二医院滨江院区消化内科,浙江杭州310000 [2]浙江大学医学院附属第二医院病理科,浙江杭州310009 [3]浙江大学医学院附属第二医院消化内科,浙江杭州310009

出　　处：《实用肿瘤杂志》2014年第5期460-462,共3页Journal of Practical Oncology

基　　金：国家公益卫生行业专项基金(200802112);国家自然基金一般项目(81372302);浙江省自然基金(Y2080001;Y12H160121);浙江省科技厅重大科技专项(2009C03012-5;2013C03044-5);浙江省卫生厅一般项目(201343550);浙江省教育厅一般项目(Y201328489)

摘　　要：重复癌是指同一宿主在同一器官或成对器官、同一系统不同部位以及不同器官同时或先后发生>2个的原发恶性肿瘤。本文报道1例下咽和食管异时性重复癌,其中下咽癌发现于食管癌术后内镜复查阶段,临床分期处于T1N0M0。已有学者建议可应用内镜下黏膜剥离术治疗早期下咽癌,有望获得良好治疗效果。因此,该重复癌病例提示内镜医生在常规胃镜检查时除仔细观察食管、胃以及十二指肠部位病变外,还应注意咽喉部特别是梨状隐窝等罕见部位的可疑早期癌变,并且可以应用新型内镜技术提高早期下咽癌的检出率,延长患者的生存期。Multiple primary carcinomas refer to two or more primary malignancies synchronously or metachronously occur in the same organ,different locations of one system or different organs in one person. One case of metachronous hypopharyngeal and esophageal multiple primary carcinomas was reported. Hypopharyngeal carcinoma was diagnosed during routine gastroscopy examine after esophageal carcinoma surgery and clinical stage was T1N0M0. Some scholars suggest endoscopic submucosal dissection for early stage hypopharyngeal carcinoma. Endoscopists should pay attention to suspicious lesions in pharynx besides esophagus,stomach and duodenum,and new techniques can be applied for the detection of early stage hypopharyngeal carcinomas.

关 键 词：食管肿瘤/外科学 下咽肿瘤/外科学 肿瘤 多原发性 内窥镜检查 

分 类 号：R735.1[医药卫生—肿瘤] R730.56[医药卫生—临床医学]